… neurodegenerative diseases, AD is the most common neurodegenerative disease. Its …
disturbance of the sleep–wake cycle and circadian rhythms, and dysfunctions of metabolism, such …

… and brainstem nuclei of the circadian–homeostatic–ultradian … in Alzheimer's disease and
Parkinson's disease. The symbol … disease; ■ predominantly affected in Parkinson's disease; ● …

… Moreover, based on evidence indicating that circadian rhythms can be challenged by …
of circadian misalignment in human pathologies, such as cancer and inflammatory diseases. …

… non-visual functions, like the control of circadian rhythms and pupil contraction, as the
cannabinoid-mediated improvement of circadian rhythmicity in P23H rats, which are mediated by …

… M10 time is an indicative measure of circadian rhythms: the higher the M10 … circadian rhythm,
an important regulator of hippocampal function, that in turn is related to neurodegeneration …

… they may reflect neurodegenerative disease in a preclinical … across years in relation to
neurodegenerative diseases 10,43 , … sleep and only indirectly reflect circadian functioning. Sixth, …

… an approach against circadian disruption in neurodegenerative diseases. In this review, we
address: circadian rhythms as an important early biomarker of neurodegenerative disorders; …

… and Parkinson disease typically develop at certain stages of life, and circadian rhythms are
… Here, we describe circadian disruptions observed in various brain disorders throughout the …

… In this study, we report that circadian rhythm disruption has profound effect on MPTP-…
common and early signs in many neurodegenerative diseases including PD. Interestingly, some …

… Under normal physiological conditions, the concentration of melatonin in humans and other
mammals fluctuates with the circadian rhythms, showing that the peak secretion at night and …