Circular RNA in disease: Basic properties and biomedical relevance

X Chen, M Zhou, L Yant… - … Reviews: RNA, 2022 - Wiley Online Library
Circular RNAs (circRNAs) represent a class of covalently closed RNA molecules with great
… Emerging advances in our understanding of circRNA biogenesis, nuclear export, and stability …

[HTML][HTML] Circular RNAs: clinical relevance in cancer

Z Xu, Y Yan, S Zeng, S Dai, X Chen, J Wei, Z Gong - Oncotarget, 2018 - ncbi.nlm.nih.gov
Circular RNAs, as recently discovered new endogenous non-coding RNAs, are important …
With the development of RNA sequencing and microarray technologies, numerous of …

The emerging role and clinical implication of human exonic circular RNA

D Lyu, S Huang - RNA biology, 2017 - Taylor & Francis
… of RNA circles, including genomic circular RNA (viroids and hepatitis delta virus), circular
intron RNA (circular intronic RNAs and … for this article, please click on the relevant link below: …

Biological roles and mechanisms of circular RNA in human cancers

Q Tang, SS Hann - OncoTargets and therapy, 2020 - Taylor & Francis
… Citation4 – Citation6 In this review, we describe the major biological functions and clinical
relevance of circRNAs, as well as its expression and regulatory mechanisms in various types …

Circular RNAs in cardiovascular disease: an overview

X Fan, X Weng, Y Zhao, W Chen… - BioMed research …, 2017 - Wiley Online Library
Circular RNA (circRNA) has been recently discovered and is becoming a research focus
in the field of untranslated RNA… which is of pathogenic relevance to ASVD susceptibility [40]. …

Circular RNAs: functions and clinical significance in cardiovascular disease

L Zhang, Y Zhang, Y Wang, Y Zhao… - Frontiers in cell and …, 2020 - frontiersin.org
… by circular RNAs (circRNAs) in the pathogenesis of CVD. CircRNAs are non-coding RNAs
… CircRNAs can function by acting as miRNA sponges, RNA binding protein sponges, mRNA …

Biogenesis and function of circular RNAs in health and in disease

G Haddad, JM Lorenzen - Frontiers in pharmacology, 2019 - frontiersin.org
Circular RNAs (circRNAs) are a class of non-coding RNA that were previously thought to be
insignificant byproducts of splicing errors. However, recent advances in RNA … of this RNA

Emerging role of circular RNA–protein interactions

A Das, T Sinha, S Shyamal, AC Panda - Non-coding RNA, 2021 - mdpi.com
… without much physiological relevance [3]… circular RNAs in exosomes [45]. This phenomenon
could further improve our understanding of exosomal circRNA, improving the use of circRNA

Circular RNAs: promising biomarkers for human diseases

Z Zhang, T Yang, J Xiao - EBioMedicine, 2018 - thelancet.com
Circular RNAs are prospective disease biomarkers due to their tissue- and development
stage-… Mechanism of circular RNAs' functions in disease development need to be clarified to …

Circular RNAs in physiology and non-immunological diseases

L Chen, C Huang, G Shan - Trends in biochemical sciences, 2022 - cell.com
… help to resolve these disputes and potentially lead to biomedical applications of circRNAs. …
], we focus here on the newly described functional relevance of individual circRNAs to normal …