Circular RNA Cdr1as sensitizes bladder cancer to cisplatin by upregulating APAF1 expression through miR‐1270 inhibition

W Yuan, R Zhou, J Wang, J Han, X Yang… - Molecular …, 2019 - Wiley Online Library
… In this study, we explored the effect of circRNA Cdr1as on the cisplatin chemosensitivity of …
is, the novel Cdr1as/miR-1270/APAF1 axis. Our results indicate that upregulated Cdr1as could …

Inhibition of circular RNA CDR1as increases chemosensitivity of 5‐FU‐resistant BC cells through up‐regulating miR‐7

W Yang, J Gu, X Wang, Y Wang, M Feng… - Journal of Cellular …, 2019 - Wiley Online Library
… This study aims to explore the mechanism of Circular RNA CDR1as implicating in regulating
5-fluorouracil (5-FU) chemosensitivity in breast cancer (BC) by competitively inhibiting miR-…

A circular twist on microRNA regulation

M Bezzi, J Guarnerio, PP Pandolfi - Cell Research, 2017 - nature.com
Circular RNAs (circRNAs) are a novel class of RNA whose … laboratories focused on a circRNA,
Cdr1as, and its ceRNA … systems, the Cdr1as circRNA is the only RNA isoform arising from …

The circular RNA CDR1as regulates the proliferation and apoptosis of human cardiomyocytes through the miR-135a/HMOX1 and miR-135b/HMOX1 axes

C Chen, H Shen, Q Huang, Q Li - Genetic testing and molecular …, 2020 - liebertpub.com
… of action of the circRNA, CDR1as, in CHF. … that circRNA CDR1as was highly expressed in
the plasma of patients with CHF. ROC analysis showed that the AUC of plasma CDR1as levels …

Circular RNA CDR1as promotes tumor progression by regulating miR-432-5p/E2F3 axis in pancreatic cancer

X Xiong, J Feng, X Yang, H Li, Q Shi, J Tao… - Cancer Cell …, 2021 - Springer
… In this research, circular RNA CDR1as (circCDR1as) was identified by microarray analysis
and detected in pancreatic cancer (PC) tissues and cells. Transwell, colony-forming assay, …

CircRNA CDR1as/miR-7 signals promote tumor growth of osteosarcoma with a potential therapeutic and diagnostic value

B Xu, T Yang, Z Wang, Y Zhang, S Liu… - Cancer management …, 2018 - Taylor & Francis
circular RNA (circRNA) antisense to the cerebellar degeneration-related protein 1 transcript
(CDR1as)/micro RNA-7(… However, the clinical role and function of CDR1as/miR-7 pathway in …

Splenic Serum Exosome Circular RNA Cdr1as Is Involved in Hepatocellular Carcinoma by Inducing Hepatic Precursor Cells EMT

Z Li, K Zhu, J Li, H Tian, J Sun, Y Guo, N Huang, B Li… - HPB, 2023 - hpbonline.org
Cdr1as is highly expressed in serum exosomes of spleen patients with … of Cdr1as in spleen
of cirrhotic mice was significantly up-regulated compared with the control group. Cdr1as can …

MyoD-induced circular RNA CDR1as promotes myogenic differentiation of skeletal muscle satellite cells

L Li, Y Chen, L Nie, X Ding, X Zhang, W Zhao… - … et Biophysica Acta (BBA …, 2019 - Elsevier
CDR1as acquired from high-throughput RNA-seq data [35], we amplified and obtained goat
CDR1as… : XM_018044065.1), using RNA derived from newborn goat muscles with divergent …

Circular RNA CDR1as sponges miR-7-5p to enhance E2F3 stability and promote the growth of nasopharyngeal carcinoma

Q Zhong, J Huang, J Wei, R Wu - Cancer cell international, 2019 - Springer
Circular RNA (circRNA) CDR1as plays an important role in the occurrence and development
… The purpose of this study is to investigate the molecular mechanism of circRNA CDR1as in …

Circular RNA and Alzheimer's disease

R Akhter - Circular RNAs: Biogenesis and Functions, 2018 - Springer
… address these objectives of circRNA detection. Recently, scientists have shown that circular
RNA is associated with brain functions. When CDR1as, an RNA molecule highly expressed …