The emerging landscape of circular RNA in life processes
… (circRNAs) are a novel class of non-coding RNA that assumes a … RNA binding proteins
(RBPs). Moreover, circRNAs have been reported to play essential roles in myriad life processes, …
(RBPs). Moreover, circRNAs have been reported to play essential roles in myriad life processes, …
[HTML][HTML] Circular RNA: metabolism, functions and interactions with proteins
WY Zhou, ZR Cai, J Liu, DS Wang, HQ Ju, RH Xu - Molecular cancer, 2020 - Springer
… circRNA-protein interactions. Hopefully, this review will help to reveal intricate circRNA-related
issues and to develop circRNA-targeted translational research and clinical applications. …
issues and to develop circRNA-targeted translational research and clinical applications. …
Circular RNA: a new star of noncoding RNAs
… CircRNAs may affect life processes, serve as diagnostic or predictive biomarkers of disease
and also provide new potential therapeutic targets. Nevertheless, compared with coding …
and also provide new potential therapeutic targets. Nevertheless, compared with coding …
Insights into circular RNA biology
… As products of a novel type of alternative splicing, circular RNAs (circRNAs) are a recently
discovered class of molecules with functional relevance for regulation of gene expression. …
discovered class of molecules with functional relevance for regulation of gene expression. …
Biogenesis and regulatory roles of circular RNAs
… A chronological view of circular RNA discoveries Another major group of circular RNA (and
the focus of this review, named circRNA hereafter) is eukaryotic specific and is produced by …
the focus of this review, named circRNA hereafter) is eukaryotic specific and is produced by …
[HTML][HTML] Circular RNA: functions, applications and prospects
M Lu - ExRNA, 2020 - Springer
… This review aims to explain the structural as well as physiochemical properties of circular
RNAs, looped mRNA molecules that have attracted recent interest with its newly discovered …
RNAs, looped mRNA molecules that have attracted recent interest with its newly discovered …
Circular RNA: an emerging key player in RNA world
… Insights into the circular RNA (circRNA) exploration have revealed that they are abundant
in eukaryotic transcriptomes. Diverse genomic regions can generate different types of …
in eukaryotic transcriptomes. Diverse genomic regions can generate different types of …
[HTML][HTML] Circular RNA-protein interactions: functions, mechanisms, and identification
A Huang, H Zheng, Z Wu, M Chen, Y Huang - Theranostics, 2020 - ncbi.nlm.nih.gov
… However, some studies have reported that the expression of a circular RNA does not
correlate with the expression of its cognate linear mRNA; in fact, under certain circumstances, …
correlate with the expression of its cognate linear mRNA; in fact, under certain circumstances, …
[HTML][HTML] Circular RNA is expressed across the eukaryotic tree of life
PL Wang, Y Bao, MC Yee, SP Barrett, GJ Hogan… - PloS one, 2014 - journals.plos.org
… of circularized RNAs containing canonical exons. Here we report that circular RNA isoforms
are … a small fraction of the theoretically possible circular RNA isoforms from a given gene are …
are … a small fraction of the theoretically possible circular RNA isoforms from a given gene are …
A 360 view of circular RNAs: From biogenesis to functions
JE Wilusz - Wiley Interdisciplinary Reviews: RNA, 2018 - Wiley Online Library
… In stark contrast, we found that the expression of many single-exon circular RNAs, including
the Laccase2 circular RNA, increased when factors with very different functions in the …
the Laccase2 circular RNA, increased when factors with very different functions in the …
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