The emerging role and clinical implication of human exonic circular RNA

D Lyu, S Huang - RNA biology, 2017 - Taylor & Francis
Circular RNA from backspliced exons (or exonic circular RNA, circRNA) is a type of covalently
closed non-colinear RNA that … role and clinical implication of these multifarious transcripts. …

The function and clinical implication of circular RNAs in lung cancer

W Ren, Y Yuan, J Peng, L Mutti, X Jiang - Frontiers in Oncology, 2022 - frontiersin.org
… that the depletion of DHX9 from nuclear RNA helicase, known to bind to … RNA accumulation
defects and increased the circular RNA production (75). ADAR1, a double-strand RNA-…

Biogenesis, functions, and clinical implications of circular RNAs in non-small cell lung cancer

Y Liu, X Ao, W Yu, Y Zhang, J Wang - Molecular Therapy-Nucleic Acids, 2022 - cell.com
… (circRNAs) are a large class of non-coding RNAs (ncRNAs) with … Moreover, we highlight
their clinical implications in NSCLC … Circular RNAs and RNA splice variants as biomarkers for …

Circular RNAs in osteoarthritis: indispensable regulators and novel strategies in clinical implications

W Zhang, L Qi, R Chen, J He, Z Liu, W Wang… - Arthritis Research & …, 2021 - Springer
Over the past decades, circular RNAs (circRNAs) have emerged as a hot spot and sparked
intensive interest. Initially considered as the transcriptional noises, further studies have …

Circular RNAs in stem cells: from basic research to clinical implications

HJ Lu, J Li, G Yang, CJ Yi, D Zhang, F Yu… - Bioscience …, 2022 - portlandpress.com
Circular RNAs (circRNAs) are a special class of endogenous RNAs with a wide variety of
pathophysiological functions via diverse mechanisms, including transcription, microRNA (…

[HTML][HTML] Circular RNAs as competing endogenous RNAs in cardiovascular and cerebrovascular diseases: molecular mechanisms and clinical implications

X Min, D Liu, X Xiong - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
Circular RNAs (circRNAs) represent a novel class of widespread and diverse endogenous
RNACircular RNAs (circRNAs) were first discovered in plant viroids more than 40 years ago (…

[PDF][PDF] Circular RNAs in the pathogenesis of sepsis and their clinical implications: a narrative review

L Wei, Y Yang, W Wang, R Xu - Ann Acad Med Singap, 2022 - annals.edu.sg
CLINICAL IMPACT What is New • This review provides an update on the understanding of
circular RNAs (circRNAs) in the pathogenesis of sepsis and the associated organ dysfunction. …

Current advances and future perspectives on the functional roles and clinical implications of circular RNAs in esophageal squamous cell carcinoma: more influential …

C Ju, J He, C Wang, J Sheng, J Jia, D Du, H Li… - Biomarker …, 2022 - Springer
Circular RNAs (circRNAs) are a type of noncoding RNAs featured by their covalently closed
circular structure. This special structure makes circRNAs more stable in mammalian cells, …

Clinical implications of circulating circular RNAs in lung cancer

SS Choi, SE Kim, SY Oh, YH Ahn - Biomedicines, 2022 - mdpi.com
RNA transcripts has also been reported in murine testis, which might prevent SRY protein
translation [11]. Circular Fmn RNA … -coding RNA in humans were proven to be circular RNAs

[HTML][HTML] Circular RNAs: clinical relevance in cancer

Z Xu, Y Yan, S Zeng, S Dai, X Chen, J Wei, Z Gong - Oncotarget, 2018 - ncbi.nlm.nih.gov
… In this review, we discuss the properties and functions of circRNAs and their clinical implication
as promising biomarkers for cancer research. Moreover, some emerging fields, such as …