Role of circular RNAs in disease progression and diagnosis of cancers: An overview of recent advanced insights

SU Khan, MU Khan, MI Khan, AA Fadahunsi… - International journal of …, 2022 - Elsevier
… Advancements have facilitated circular RNA discovery and investigation in high-throughput
sequencing and computational techniques [5], [204]. There are numerous ways in which …

Circular RNAs: Characteristics, functions, mechanisms, and potential applications in thyroid cancer

M Wu, H Yuan, W Zou, S Xu, S Liu, Q Gao… - Clinical and …, 2024 - Springer
… Subsequently, the debranching enzyme 1 (DBR1) acts on this structure, resulting in a circular
RNA … Such insights could be pivotal in elucidating the clinical implications of these putative …

Circular RNA in cardiovascular disease

MA Altesha, T Ni, A Khan, K Liu… - Journal of cellular …, 2019 - Wiley Online Library
Circular RNAs (circRNA) are single stranded RNAs that form a covalently closed loop
without free terminals. Many circRNAs are endogenous, stable, abundant, and exhibit cell type, …

The emerging landscape of circular RNA ciRS-7 in cancer

L Peng, XQ Yuan, GC Li - Oncology reports, 2015 - spandidos-publications.com
… In March 2013, two publications reported that circular RNAs (circRNAs) function as miRNA
‘sponges’ that act to naturally sequester and competitively suppress the activity of miRNAs (13…

The role of circular RNAs in immune-related diseases

R Xie, Y Zhang, J Zhang, J Li, X Zhou - Frontiers in Immunology, 2020 - frontiersin.org
… Studying the relationships between circRNAs and diseases has important clinical implications,
including but not limited to discoveries related to pathological roles, diagnostic potential, …

Circular RNAs in Alzheimer's disease: A new perspective of diagnostic and therapeutic targets

O Vakili, P Asili, Z Babaei, M Mirahmad… - CNS & Neurological …, 2023 - ingentaconnect.com
… AND circular RNAs”, “Alzheimer disease AND circular RNAs”, “circular RNAs AND … LncRNAs
are further subdivided into linear RNAs and circular RNAs (circRNAs) [60]. In comparison to …

Circular RNAs open a new chapter in cardiovascular biology

S Aufiero, YJ Reckman, YM Pinto… - Nature Reviews …, 2019 - nature.com
Circular RNAs (circRNAs) are emerging as a new class of non-coding RNA molecules. This
… 1: Schematic representation showing the three mechanisms for circular RNA biogenesis. …

Role of circular RNAs in brain development and CNS diseases

SL Mehta, RJ Dempsey, R Vemuganti - Progress in neurobiology, 2020 - Elsevier
… Recent studies have identified a new class of ncRNAs called circular RNAs (circRNAs),
which are produced by back-splicing and fusion of either exons, introns, or both exon-intron into …

Function and clinical significance of circular RNAs in thyroid cancer

X Yao, Q Zhang - Frontiers in molecular biosciences, 2022 - frontiersin.org
circular RNAs (circRNAs). circRNAs with covalently closed single-stranded structures have
been identified as a type of regulatory RNAclinical implications of specific circRNAs in TC. …

Circular RNA expression profile of Alzheimer's disease and its clinical significance as biomarkers for the disease risk and progression

Y Li, H Fan, J Sun, M Ni, L Zhang, C Chen… - … International Journal of …, 2020 - Elsevier
… Our study provides an overview of circRNA expression profile in AD, and identifies that
circ-AXL, circ-GPHN and circ-PCCA hold clinical implications for guiding disease management in …