Circular RNAs in cancer: biogenesis, function, and clinical significance

J Li, D Sun, W Pu, J Wang, Y Peng - Trends in cancer, 2020 - cell.com
Circular RNA (circRNA) is a class of single-stranded molecules with tissue/development-specific
expression patterns. Unlike linear RNA… resistance to exonucleolytic RNA decay. …

Circular RNAs: characteristics, function and clinical significance in hepatocellular carcinoma

M Wang, F Yu, P Li - Cancers, 2018 - mdpi.com
Circular RNAs (circRNAs), a class of long-overlook non-coding RNA, have been revealed
as multi-functional RNAs in recent years. Growing evidence indicates that circRNA expression …

[HTML][HTML] Circular RNAs: clinical relevance in cancer

Z Xu, Y Yan, S Zeng, S Dai, X Chen, J Wei, Z Gong - Oncotarget, 2018 - ncbi.nlm.nih.gov
Circular RNAs, as recently discovered new endogenous non-coding RNAs, are important …
With the development of RNA sequencing and microarray technologies, numerous of …

Circular RNAs in hepatocellular carcinoma: Emerging functions to clinical significances

Y Zhang, Y Wang - Frontiers in oncology, 2021 - frontiersin.org
Circular RNAs (circRNAs) are a class of non-coding RNAs with covalently closed loop
structures. They are characterized by remarkable stability, long half-life, abundance and …

Circular RNAs in cell cycle regulation: Mechanisms to clinical significance

W Xiao, J Li, J Hu, L Wang, JR Huang, G Sethi… - Cell …, 2021 - Wiley Online Library
Circular RNAs (circRNAs), a type of non‐coding RNA, are single‐stranded circularized
molecules characterized by high abundance, evolutionary conservation and cell development‐ …

Circular RNAs in prostate cancer: Biogenesis, biological functions, and clinical significance

X Liu, Y Tong, D Xia, E Peng, X Yang, H Liu… - … Therapy-Nucleic Acids, 2021 - cell.com
Circular RNAs (circRNAs) are covalently closed RNA molecules that play important regulatory
roles in various tumors. Prostate cancer (PCa) is one of the most common malignant …

[HTML][HTML] The biogenesis, function and clinical significance of circular RNAs in breast cancer

Y Zeng, Y Zou, G Gao, S Zheng, S Wu… - Cancer biology & …, 2022 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are noncoding RNAs that form covalently closed loop structures.
CircRNAs are dysregulated in cancer and play key roles in tumorigenesis, diagnosis, and …

Functions and clinical significance of circular RNAs in glioma

J Sun, B Li, C Shu, Q Ma, J Wang - Molecular cancer, 2020 - Springer
… Multiple hnRNP (heterogeneous nuclear ribonucleoprotein) and SR (serine–arginine)
proteins regulated Laccase circular RNA levels that are not controlled by MBL in a combinatorial …

Circular RNA: functions, applications and prospects

M Lu - ExRNA, 2020 - Springer
… This review aims to explain the structural as well as physiochemical properties of circular
RNAs, looped mRNA molecules that have attracted recent interest with its newly discovered …

Circular RNAs in sepsis: biogenesis, function, and clinical significance

J Beltran-Garcia, R Osca-Verdegal, E Nacher-Sendra… - Cells, 2020 - mdpi.com
… Despite more than 170 different biomarkers being postulated, early sepsis diagnosis and
prognosis remain a challenge for clinicians. Recent findings propose that circular RNAs (…