Integrative network analysis of circular RNAs reveals regulatory mechanisms for hepatic specification of human iPSC-derived endoderm

F Bai, J Duan, D Yang, X Lai, X Zhu, X He… - Stem Cell Research & …, 2022 - Springer
… profiles of circRNAs during hepatic specification. We identified … hepatic specification. These
results provide novel insight into the molecular mechanisms involved in hepatic specification

[HTML][HTML] Screening differential circular RNA expression profiles reveals hsa_circ_0004018 is associated with hepatocellular carcinoma

L Fu, T Yao, Q Chen, X Mo, Y Hu, J Guo - Oncotarget, 2017 - ncbi.nlm.nih.gov
… As shown in Figure ​2E, compared with human normal hepatic cell line L02, we found that
the … Concentration and purity of total RNA samples were measured by the Smart Spec Plus …

[HTML][HTML] Expanded expression landscape and prioritization of circular RNAs in mammals

P Ji, W Wu, S Chen, Y Zheng, L Zhou, J Zhang… - Cell reports, 2019 - cell.com
Circular RNAs (circRNAs) are emerging as essential regulators of various biological and
disease processes. To comprehensively understand the diversity of circRNAs and prioritize …

Genome-wide identification and characterization of circular RNA in resected hepatocellular carcinoma and background liver tissue

Y Sunagawa, S Yamada, F Sonohara, K Kurimoto… - Scientific reports, 2021 - nature.com
… Zhou et al. showed that expression profiles for hepatic circRNAs were significantly
different between chronic hepatitis B (CHB) and normal hepatic tissues, with 99 dysregulated …

The role of circular RNA hsa_circ_0085616 in proliferation and migration of hepatocellular carcinoma cells

W Li, X Zhou, X Wu, J Wei, Z Huang - Cancer management and …, 2019 - Taylor & Francis
… Further analysis was performed in different HCC cell lines and human normal hepatic
cell lines. Moreover, we down- or upregulated its expression by cell transfection in vitro. Cell …

Circulating long and circular noncoding RNA as non-invasive diagnostic tools of hepatocellular carcinoma

CHC Sukowati, LKD Cabral, C Tiribelli, D Pascut - Biomedicines, 2021 - mdpi.com
… Here, we review data on how various long noncoding RNAs (lncRNAs) and circular RNAs
(… Plasma MALAT1 was up-regulated in HCC compared to hepatic diseases (chronic viral …

DETECTION OF CIRCULAR RNAS IN HEPATOCELLULAR CARCINOMA TREATED WITH DIFFERENT THERAPEUTIC AGENTS USING RNA-SEQ DATA

B Tamkoç - 2021 - open.metu.edu.tr
… for circular isoforms. However, it is also possible to detect circular RNAs from regular RNA-…
The aim of this thesis is to detect circular RNAs from the raw RNA-Seq data and to analyze …

Hsa‑circRNA‑G004213 promotes cisplatin sensitivity by regulating miR‑513b‑5p/PRPF39 in liver cancer Corrigendum in/10.3892/mmr. 2021.12359

L Qin, Z Zhan, C Wei, X Li… - Molecular medicine …, 2021 - spandidos-publications.com
… has confirmed that exosomal circular RNAs (circRNAs) serve a … Globally, liver cancer (LC)
is the commonest type of hepatic … LC was diagnosed according to the 2017 specifications for …

A tumor-suppressive circular RNA mediates uncanonical integrin degradation by the proteasome in liver cancer

L Shi, B Liu, D Shen, P Yan, Y Zhang, Y Tian, L Hou… - Science …, 2021 - science.org
Circular RNAs (circRNAs) are noncoding RNAs usually produced from back-splicing of exons
of pre-mRNAs. They are usually present in the cytoplasm and relatively stable, functioning …

[HTML][HTML] Noncoding RNAs as additional mediators of epigenetic regulation in nonalcoholic fatty liver disease

M Zaiou - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
… Noncoding RNAs (ncRNAs), including microRNAs, long noncoding RNAs, and circular RNAs,
… Moreover, miR-21 plays a key role in hepatic lipid metabolism by promoting hepatic lipid …