[HTML][HTML] Circular RNAs modulate cancer hallmark and molecular pathways to support cancer progression and metastasis

AA Yarmishyn, AA Ishola, CY Chen, ND Verusingam… - Cancers, 2022 - mdpi.com
Simple Summary Circular RNAs (circRNA) are a type of RNA molecule of circular shape that
are now being extensively studied due to the important roles they play in different biological …

[HTML][HTML] Functions and clinical significance of circular RNAs in glioma

J Sun, B Li, C Shu, Q Ma, J Wang - Molecular cancer, 2020 - Springer
… In this review, we elaborate on the biogenesis, functions, databases as well as novel
advances especially involved in the molecular pathways, highlight its great value as diagnostic or …

[HTML][HTML] Circular RNAs: emerging regulators of the major signaling pathways involved in cancer progression

M Papatsirou, PI Artemaki, P Karousi, A Scorilas… - Cancers, 2021 - mdpi.com
circular RNAs (circRNAs) have emerged as key molecules in this context that interact
multifariously with major signaling pathways… conserved, single-stranded RNA molecules that form …

[HTML][HTML] Advances in circular RNAs and their roles in breast Cancer

X Wang, L Fang - Journal of Experimental & Clinical Cancer Research, 2018 - Springer
Circular RNAs (circRNAs) are a type of noncoding RNAs with a closed loop structure. With
… It is vital to understand the molecular pathways involved in the pathogenesis of proliferation …

Circular RNAs and cancer

J He, Q Xie, H Xu, J Li, Y Li - Cancer letters, 2017 - Elsevier
… transcriptome and non-coding RNA but also provide new ideas … circular RNA molecules
to silence important binding sites associated with cancer. We can also target specific molecular

The expanding regulatory mechanisms and cellular functions of circular RNAs

LL Chen - Nature reviews Molecular cell biology, 2020 - nature.com
… Many protein-coding genes in higher eukaryotes can produce circular RNAs (circRNAs) …
to interfere with microRNA activities or signalling pathways, and serving as templates for …

[HTML][HTML] The emerging roles and functions of circular RNAs and their generation

CY Yu, HC Kuo - Journal of biomedical science, 2019 - Springer
… to regulate proliferation through effects on signaling pathways, transcription factors and
cell cycle checkpoint regulators. Two major pathways that regulate cell proliferation and are …

[HTML][HTML] Circular RNAs function as ceRNAs to regulate and control human cancer progression

Y Zhong, Y Du, X Yang, Y Mo, C Fan, F Xiong, D Ren… - Molecular cancer, 2018 - Springer
Circular RNAs (circRNAs) are connected at the 3′ and 5′ ends by exon or intron cyclization,
forming a complete ring structure. circRNA is more stable and conservative than linear …

Circular RNAs (circRNAs) in cancer

R Zhou, Y Wu, W Wang, W Su, Y Liu, Y Wang, C Fan… - Cancer letters, 2018 - Elsevier
… circRNAs can affect the proliferation of cells by regulating various molecules in this pathway
downstream molecules (cyclin A and CDK2) that are related to the Wnt/β-Catenin pathway

Circular RNAs: identification, biogenesis and function

KK Ebbesen, J Kjems, TB Hansen - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
… regulators, illustrating the relevance of circular RNAs as participants in the regulatory …
that characterize circular RNAs, discuss putative circular RNA biogenesis pathways as well …