… When compared to the available information for patients on dialysis (CKD stage 5D), data …
calcium and phosphate metabolism in the predialysis stages of chronic kidney disease (CKD) …

… This study involved 90 phosphate binder-naive patients with CKD stages 3–5 who were not
… ) to either a low-phosphate diet alone, or to a low-phosphate diet in combination with fixed …

… that iron metabolism is dysregulated in CKD patients [10]. Dysregulated iron metabolism
readily … We suspected that hyperphosphatemia and dysregulation of iron metabolism could …

… phosphate metabolism in CKD, and that αKlotho and FGF23 are involved in the pathophysiology
as well as the onset of complications and survival in CKD… phosphate metabolism in CKD…

… hyperphosphataemia are advanced stages of CKD, acute kidney injury, phosphate supplements
with or without vitamin D supplements, hypoparathyroidism, metabolic and respiratory …

… during CKD progression, 5 indicating that dysregulation of phosphate metabolism
ensues in early-stage CKD long before there is an increase in blood phosphate levels. …

… level in early stages of CKD, but in more advanced CKD, these … in CKD, likely in response
to abnormal PO 4 metabolism, … PO 4 levels to normal in CKD stage 3 and in early stage 4. The …

… with CKD, diabetes, coronary artery disease, or even normal adults. In patients with CKD stage
… are limited data regarding the role of phosphate binders in these patients. Recent studies …

… an increase in PTH are the earliest mineral metabolism alterations in CKD, while serum
calcium and phosphate are altered later in the course of CKD. The percentages of patients with …

… Practice Guidelines for Bone Metabolism and Disease recommend that serum phosphate
levels be maintained between 2.7 and 4.6 mg per 100 ml in patients with CKD stages 3 and 4, …