… with severe malaria. To characterize the clearance kinetics of parasitized erythrocytes and
malaria … were assessed in 27 adult Vietnamese patients with severe falciparum malaria. The …

… Severe malaria is a consequence of a failure of the infecting parasites to stop multiplying [13…
parasite clearance following chloroquine compared with quinine treatment of severe malaria …

… Severe malaria in children most often manifests as either a … Parasite clearance kinetics link
the three themes discussed in … of rapid parasite clearance; pharmacokinetics and dosing in …

… kinetics of blood-stage parasitemia in malaria-naïve volunteers and parasite clearance
kinetics … by DVI and characterized parasite clearance dynamics following treatment with the …

… to evaluate malaria parasite clearance following treatment of patients with severe malaria …
, and route of drug administration in addition to parasite resistance, affect clearance kinetics …

… associated with faster parasite clearance, lower insulin… severe malaria mainly results from
enhanced anaerobic glycolysis. Quinine differs from artesunate in its effects on glucose kinetics…

Background Severe malaria is a medical emergency with high mortality. Prompt achievement
of therapeutic concentrations of highly effective anti-malarial drugs reduces the risk of …

… ACTs remain largely effective in clearing malaria infections, but reduced parasite clearance
rates (ie… Parasite clearance rates have also been used to evaluate the likely clinical impact of …

… We observed the development of this degree of anemia with low parasite burdens in semi-immune
BALB/c mice and in naive Wistar rats infected with P berghei ANKA, with kinetic …

… The lag time between drug administration and the start of parasite clearance reflects both
pharmacokinetic (absorption and distribution) and pharmacodynamic (rapidity of action and …