Clinical and genetic characterization of de novo double-hit B cell precursor leukemia/lymphoma

JA Stratmann, AB von Rose, S Koschade… - Annals of …, 2019 - Springer
… Here, we report the clinical and genetic characteristics of 6 cases of de novo acute B cell
precursor leukemia that harbored combined MYC and BCL2 and/or BCL6 rearrangements (DH/…

[HTML][HTML] Clinical and genetic characteristics of children with acute lymphoblastic leukemia and Li–Fraumeni syndrome

G Winter, R Kirschner-Schwabe, S Groeneveld-Krentz… - Leukemia, 2021 - nature.com
Clinical features were in agreement with reported findings [2]. All patients had B-cell
precursor … The analysis of common leukemia fusion genes showed a BCR/ABL and ETV6/RUNX1 …

[HTML][HTML] Clinical and Genetic Characteristics of IKZF1 Mutation in Chinese Children With B-Cell Acute Lymphoblastic Leukemia

J Zhang, XJ Xu, L Liu, H Song, H Shen, W Xu… - … in Genetics, 2022 - frontiersin.org
… Here, we systematically analyzed the clinical and genetic characteristics of Chinese B-ALL
children with IKZF1 mutation in our single center. These data may provide evidence for risk …

[HTML][HTML] Clinical and genetic features of pediatric acute lymphoblastic leukemia in Down syndrome in the Nordic countries

C Lundin, E Forestier, M Klarskov Andersen… - Journal of hematology & …, 2014 - Springer
… Their clinical and genetic features were compared with those of the 4,647 B-cell precursor
(… The present study adds further support for genetic and clinical differences between DS-ALL …

Cytogenetic and molecular genetic characterization of the'high hyperdiploid'B-cell precursor acute lymphoblastic leukaemia cell line MHH-CALL-2 reveals a near …

HE Aburawi, A Biloglav, B Johansson… - British journal of …, 2011 - search.ebscohost.com
… divided according to the prognostic and clinical features based on acquired genetic aberrations.
It also presents a genetic study of MHH-CALL-2 cell line relevent for the analysis of ALL. …

136. Rare but recurrent translocations, Clustered Genomic Aberrations in Early T-cell Precursor Acute Lymphoblastic Leukemia

A Yenamandra, Y Akgun, S Zarnegar, K Zhao… - Cancer Genetics, 2022 - Elsevier
Clinically significant gene fusion transcripts have been reported due to chromoanagenesis
itself. We present two cases of early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) …

IKZF1 deletion is associated with a poor outcome in pediatric B‐cell precursor acute lymphoblastic leukemia in Japan

D Asai, T Imamura, S Suenobu, A Saito… - Cancer …, 2013 - Wiley Online Library
… Second, our genetic analysis carried out in this study was not comprehensive. For example,
we were not able to analyze the IgH@-CRLF2 fusion due to lack of the materials for FISH …

[PDF][PDF] Cytogenetic and molecular genetic characterization of the 'high hyperdiploid'B-cell precursor acute lymphoblastic leukaemia...

A Biloglav, K Paulsson - 2011 - academia.edu
… Cytogenetic and molecular genetic characterization of the ‘high hyperdiploid’ B-cell
precursor acute lymphoblastic leukaemia cell line MHH-CALL-2 reveals a near-haploid origin …

[HTML][HTML] Characterization of pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia with kinase fusions in Japan

T Imamura, N Kiyokawa, M Kato, C Imai… - Blood cancer …, 2016 - nature.com
… The present study aimed to clarify the clinical characteristics of Philadelphia-negative
BCP-… a genetic analysis of pediatric BCP-ALL to identify patients with kinase fusions. Clinical

[HTML][HTML] Molecular basis and clinical significance of genetic aberrations in B-cell precursor acute lymphoblastic leukemia

F Ghazavi, T Lammens, N Van Roy, B Poppe… - Experimental …, 2015 - Elsevier
… Recent developments in genomewide genetic analysis have provided a wide range of
chromosomal and genomic abnormalities characterizing BCP-ALL, several of which are …