… A breakthrough will be achieved when an in-depth genetic characterization of T-ALL allows
us to distinguish distinct immunophenotypic/genomic profiles, properly classifying the unique …

… In the present study, we aimed to obtain a clinical and genetic profile of a relatively large
cohort of wild-type MLL infant ALL patients all treated according to INTERFANT treatment …

Intrachromosomal amplification of chromosome 21 (iAMP21) defines a distinct subgroup of
childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) that has a dismal …

… This study suggests that particular Ig and TCR genotypes may be of clinical relevance in
childhood B-cell precursor ALL. The finding of rearranged TCR genes in a large proportion of …

… pathway genes were detected by whole exome analysis in … genes consist of a distinct
subgroup of B-cell precursor acute … immunophenotype, while the clinical features depend on the …

… Our own findings in B-cell precursor ALL further supports the concept that ALL may arise in
a hemopoietic cell with a less mature phenotype than committed B-lineage cells. However, in …

… Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) has been identified as high-…
and the clinical course we assessed molecular alterations and clinical characteristics in a …

… genetic heterogeneity within pediatric high-risk B-precursor acute lymphoblastic leukemia
(ALL), a clinically … cytogenetic abnormalities, we performed gene expression profiling in a …

… in a high frequency in early T-cell precursor ALL, which are characterized not only by their
immature … We conclude that BAL patients are most notably characterized by various genetic …

… to infant B-cell precursor acute lymphoblastic leukemia. (A) … analysis of gene expression
of infant B-cell precursor acute … the top 1,000 variably expressed genes, as determined by …