The clinical relevance of chromosomal and genomic abnormalities in B-cell precursor acute lymphoblastic leukaemia
AV Moorman - Blood reviews, 2012 - Elsevier
… The discovery and characterisation of genetic abnormalities have increased our … the
main genetic abnormalities which are used to manage patients with B-cell precursor ALL and …
main genetic abnormalities which are used to manage patients with B-cell precursor ALL and …
Cytogenetic and molecular characteristics and outcomes of adult patients with early T‐cell precursor acute lymphoblastic leukemia
JH Yoon, HS Kim, GJ Min, SS Park… - European Journal of …, 2023 - Wiley Online Library
… chemotherapy were included in this retrospective analysis. All of them had adequate
immunophenotype data with suitable materials for genetic analysis. Diagnosis of T-ALL was done …
immunophenotype data with suitable materials for genetic analysis. Diagnosis of T-ALL was done …
Clinical and cytogenetic features of pediatric dic (9; 20)(p13. 2; q11. 2)‐positive B‐cell precursor acute lymphoblastic leukemias: a Nordic series of 24 cases and …
E Forestier, F Gauffin, MK Andersen… - Genes …, 2008 - Wiley Online Library
… B-cell precursor acute lymphoblastic leukemias (BCP ALL), little is known about its clinical
impact … We here review the clinical and cytogenetic features of a Nordic pediatric series of 24 …
impact … We here review the clinical and cytogenetic features of a Nordic pediatric series of 24 …
[HTML][HTML] Clinical and molecular characteristics of MEF2D fusion-positive B-cell precursor acute lymphoblastic leukemia in childhood, including a novel translocation …
K Ohki, N Kiyokawa, Y Saito, S Hirabayashi… - …, 2019 - ncbi.nlm.nih.gov
… , mutually exclusive of the common risk stratifying genetic abnormalities, although their true
incidence and associated clinical characteristics remain unknown. We identified 16 cases of …
incidence and associated clinical characteristics remain unknown. We identified 16 cases of …
[HTML][HTML] … of residual disease in pediatric B-cell precursor acute lymphoblastic leukemia by comparative phenotype mapping: a study of five cases controlled by genetic …
MN Dworzak, F Stolz, G Fröschl, D Printz, T Henn… - Experimental …, 1999 - Elsevier
… We recently investigated samples of pediatric B-cell precursor acute lymphoblastic leukemia
(BCP-ALL) and normal bone marrow (BM). We found that leukemic blasts, compared to …
(BCP-ALL) and normal bone marrow (BM). We found that leukemic blasts, compared to …
Molecular genetic characterization reveals new subsets of mantle cell lymphoma
EF Thelander, R Rosenquist - Leukemia & lymphoma, 2008 - Taylor & Francis
… heavy-chain variable (IGHV) gene analysis; a major subset with unmutated IGHV genes
and a smaller subset (∼20 to 30%) displaying mutated IGHV genes. Presence of somatic …
and a smaller subset (∼20 to 30%) displaying mutated IGHV genes. Presence of somatic …
[HTML][HTML] New biological and genetic classification and therapeutically relevant categories in childhood B-cell precursor acute lymphoblastic leukemia
J Starý, J Zuna, M Zaliova - F1000Research, 2018 - ncbi.nlm.nih.gov
… further dissected and better characterized. This review focuses on recent findings related
to five novel BCP-ALL subtypes and selected clinically relevant genetic aberrations/patterns. …
to five novel BCP-ALL subtypes and selected clinically relevant genetic aberrations/patterns. …
[HTML][HTML] Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features
… Little is known of the relationship between different cytogenetic subtypes in B-cell precursor
… associated genes. In a consecutive series of 1427 childhood B-cell precursor acute …
… associated genes. In a consecutive series of 1427 childhood B-cell precursor acute …
Biological, functional and genetic characterization of bone marrow-derived mesenchymal stromal cells from pediatric patients affected by acute lymphoblastic …
A Conforti, S Biagini, F Del Bufalo, P Sirleto… - PLoS …, 2013 - journals.plos.org
… children had B-cell precursor ALL. Table 1 details patient characteristics at diagnosis. MSCs
… Our data on the genetic characterization of MSCs show for the first time that MSCs isolated …
… Our data on the genetic characterization of MSCs show for the first time that MSCs isolated …
Early events in human T cell ontogeny. Phenotypic characterization and immunohistologic localization of T cell precursors in early human fetal tissues.
BF Haynes, ME Martin, HH Kay… - The Journal of …, 1988 - rupress.org
… We found that before T cell precursor colonization of the thymus (7-8 wk of gestation), CD7'
cells were present in yolk sac, neck, upper thorax, and fetal liver, and were concentrated in …
cells were present in yolk sac, neck, upper thorax, and fetal liver, and were concentrated in …