… :female ratio: 1.43:1) diagnosed with B-cell precursor ALL at age 1–17 years (median: 5 years…
Baseline genetic characterization of patient samples included DNA index measurement by …

… The present study aimed to clarify the clinical characteristics of Philadelphia-negative
BCP-… a genetic analysis of pediatric BCP-ALL to identify patients with kinase fusions. Clinical …

… Several recurrent genetic lesions are associated with distinct risk profiles of pediatric B-cell
precursor acute lymphoblastic leukemia (BCP ALL) and are hence used for treatment …

… In the current study we provide the first analysis and characterization of the expression …
of tumour cells in relapsed B cell precursor ALL. The analysis focuses on growth factors which …

… analysis has been instrumental for the identification of genetic alterations in B-cell precursor
… Notably, some of these genetic defects have been associated with poor treatment outcome …

… Therefore, we investigated the clinical relevance of 13 recurrent genetic alterations in 204
children treated uniformly for relapsed B-cell precursor ALL according to the ALL-REZ BFM …

Childhood B-cell precursor (BCP) ALL is thought to be caused by a delayed immune response
to an unidentified postnatal infection. An association between BCP ALL and HLA class II (…

… of IKZF1 gene deletion (IKZF1 del ) as a stratifying criterion in B-cell precursor acute
lymphoblastic leukemia (BCP-ALL) is still debated. We performed a comprehensive analysis of the …

… of the gene set associated with early T-cell precursor (ETP) T-ALL was analyzed by Gene
Set Enrichment Analysis using the Student t test metric and 10 000 permutations of the genes. …

… with diverse clinical genetics by single-cell mass cytometry and compared the profiles to
those of BM aspirates from five healthy donors (hereafter referred to as healthy BM (Fig. 1a and …