… review discusses the benefits of antenatal MgSO 4 administration for fetal neuroprotection. …
of fetal/infant death or cerebral palsy in the analysis of the 4 trials with fetal neuroprotective …

… Clinical trials of neuroprotective agents present unique challenges in the newborn. Despite
… , neuroprotective interventions have for the most part performed poorly in clinical trials. This …

… to have the most potential for clinical applications. They can be … not be the way the
neuroprotective mechanism worked. The … Recent animal experiments have shown that the …

… the evidence for the neuroprotective effects of MgSO 4 on the … of the RCTs and/or other
original clinical studies; 3) analyze the … MgSO 4 treatment for fetal neuroprotection since 2010 in …

… Evaluating clinically used and novel fetal neuroprotective measures is essential for …
consequences of fetal brain injury. Magnesium sulfate is a clinical fetal neuroprotective agent utilized …

… treatments continues; we discuss neuroprotective agents (erythropoietin, N-… neuroprotection
in animal models. ► We discuss clinical trials of therapeutic approaches to neuroprotection…

… are instituted after termination of the insult, an important clinical point. Of the potential
interventions, the leading candidates for application to the human infant in the relative short-term …

… valuable clinical application in the protection from HIE. If this intervention is effective clinically
… [53], it could provide a clinically safe therapeutic intervention in a population not eligible for …

… -clinical animal models, pilot clinical studies, or both as treatments for: (1) antenatal therapy
for fetuses with a diagnosis of antenatal fetal … and clinical translation of novel neuroprotective …

… neuroprotection could soon become clinical … clinical trials are still required. There is also
great potential to augment hypothermic neuroprotection with co-administered neuroprotective …