Development and clinical application of a LC-MS/MS method for simultaneous determination of various tyrosine kinase inhibitors in human plasma

L Götze, A Hegele, SK Metzelder, H Renz… - Clinica Chimica …, 2012 - Elsevier
… Quite recently also high sensitive simultaneous determination of nine TKIs by ultra
performance LC/MS-MS was reported [22] while many clinical laboratories use a common liquid …

… for the simultaneous determination of 6‐cyanodopamine, 6‐nitrodopamine, 6‐nitrodopa, 6‐nitroadrenaline and 6‐bromodopamine in human plasma and its clinical …

LF Ribeiro, T Babadopulos… - Biomedical …, 2024 - Wiley Online Library
The aim of this study was to develop a high‐performance liquid chromatography–tandem
mass spectrometry method for the determination of 6‐cyanodopamine, 6‐nitrodopamine, 6‐…

Development and clinical application of high performance liquid chromatography for the simultaneous determination of plasma levels of theophylline and its …

J Kizu, S Watanabe, N Yasuno… - Biomedical …, 1999 - Wiley Online Library
A high performance liquid chromatography (HPLC) method has been developed for the
simultaneous determination of plasma levels of theophylline and its metabolites without …

Simultaneous determination of β2‐agonists in human urine by fast‐gas chromatography/mass spectrometry: method validation and clinical application

D Di Corcia, V Morra, M Pazzi… - Biomedical …, 2010 - Wiley Online Library
… developed and validated for the simultaneous determination of 15 b2-agonists … simultaneously,
while keeping the procedure simple and reliable. Validation parameters were determined

… simultaneous determination of voriconazole and its N-oxide in human plasma using an isocratic high-performance liquid chromatography method and its clinical …

T Yamada, Y Mino, T Yagi, T Naito, J Kawakami - Clinical biochemistry, 2012 - Elsevier
… The aim of this study was to develop a simultaneous determination method for voriconazole
(VRCZ) and its N-oxide (VNO) in human plasma and to apply it to clinical samples. …

Validation and clinical application of an UHPLC method for simultaneous analysis of total homocysteine and cysteine in human plasma

A Valente, MR Bronze, M Bicho… - Journal of separation …, 2012 - Wiley Online Library
… The validation and clinical application of an ultra HPLC method for analysis of Hcy and L-Cys
is described. The reported method is simple, sensitive, rapid, precise, and less aggressive …

… validations and clinical applications of a miniaturized, simple and cost-effective solid phase extraction combined with LC-MS/MS for the simultaneous determination of …

XS Li, S Li, G Kellermann - Talanta, 2016 - Elsevier
It remains a challenge to simultaneously quantify catecholamines and metanephrines in a
simple, sensitive and cost-effective manner due to pre-analytical and analytical constraints. …

Simultaneous determination of sibutramine and its N-desmethyl metabolites in human plasma by liquid chromatography–electrospray ionization–mass spectrometry …

L Ding, X Hao, X Huang, S Zhang - Analytica chimica acta, 2003 - Elsevier
A sensitive liquid chromatography–electrospray ionization–mass spectrometry (LC–ESI–MS)
method for simultaneous determination of sibutramine and its two active N-desmethyl …

Simultaneous determination of flurbiprofen and its hydroxy metabolite in human plasma by liquid chromatography-tandem mass spectrometry for clinical application

HI Lee, CI Choi, JY Byeon, JE Lee, SY Park… - … of chromatography B, 2014 - Elsevier
Flurbiprofen (FLB) is one of the phenylalkanoic acid derivatives of non-steroidal anti-inflammatory
drugs used for the management of pain and inflammation in patients with arthritis. We …

Simultaneous determination of vitamins A, E and 25-OH-vitamin D: Application in clinical assessments

F Granado-Lorencio, B Olmedilla-Alonso… - Clinical …, 2006 - Elsevier
… used for the simultaneous determination of vitamins A and E … it applicable to the simultaneous
determination of 25-OH-… interest and ensure the detection of clinically relevant values of 25-…