DNA methylation based biomarkers: practical considerations and applications
AH Kit, HM Nielsen, J Tost - Biochimie, 2012 - Elsevier
… , which is of great potential for many applications. This stable … In some cases, DNA methylation
based biomarkers have … is to discuss the advantages of DNA methylation as a biomarker, …
based biomarkers have … is to discuss the advantages of DNA methylation as a biomarker, …
Molecular diagnostic applications of DNA methylation technology
SE Cottrell - Clinical biochemistry, 2004 - Elsevier
… analysis of patterns of methylation across the genome … DNA methylation-based molecular
diagnostic assays are particularly attractive because of the stability of the target analyte (DNA…
diagnostic assays are particularly attractive because of the stability of the target analyte (DNA…
Profiling DNA methylation based on next-generation sequencing approaches: new insights and clinical applications
D Barros-Silva, CJ Marques, R Henrique, C Jerónimo - Genes, 2018 - mdpi.com
… DNA methylation profiles can also be inherited through cell division … DNA methylation to
answer biological questions has been highlighted. Moreover, uncovering of DNA methylation …
answer biological questions has been highlighted. Moreover, uncovering of DNA methylation …
Clinical applications of DNA methylation biomarkers in colorectal cancer
… In recent years, abnormal patterns of DNA methylation have … of DNA methylation biomarkers
in CRC clinical applications. … blood-based MLH1 DNA methylation assay. Another example …
in CRC clinical applications. … blood-based MLH1 DNA methylation assay. Another example …
DNA methylation biomarkers in colorectal cancer: Clinical applications for precision medicine
N Fatemi, S Tierling, HA Es, M Varkiani… - … journal of cancer, 2022 - Wiley Online Library
… Hence, the drugs that inhibit DNA methylation must be … highlight clinical applications of DNA
methylation biomarkers … expanding evidence that supports DNA methylation changes as a …
methylation biomarkers … expanding evidence that supports DNA methylation changes as a …
A summary of the biological processes, disease-associated changes, and clinical applications of DNA methylation
GB Andersen, J Tost - DNA Methylation Protocols, 2018 - Springer
… pathologies for which changes in DNA methylation patterns have been investigated will be
… much of the DNA methylation literature on clinical applications of DNA methylation changes …
… much of the DNA methylation literature on clinical applications of DNA methylation changes …
Quantitative comparison of DNA methylation assays for biomarker development and clinical applications
Nature biotechnology, 2016 - nature.com
… DNA methylation assays that are sufficiently fast, cheap, robust and widely available to be
useful for routine clinical … for measuring DNA methylation in large cohorts, clinical diagnostics …
useful for routine clinical … for measuring DNA methylation in large cohorts, clinical diagnostics …
DNA methylation-based predictors of health: applications and statistical considerations
… of DNA methylation-based predictors across a wide range of health-related applications,
from the … This Review evaluates the progress of existing DNA methylation-based predictors, …
from the … This Review evaluates the progress of existing DNA methylation-based predictors, …
Cancer DNA methylation: molecular mechanisms and clinical implications
MT McCabe, JC Brandes, PM Vertino - Clinical Cancer Research, 2009 - AACR
… Thus far, clinical applications of epigenetic therapy have primarily focused on nucleoside
analog inhibitors of the DNMTs, alone (95) and in combination with HDAC inhibitors (95–98). …
analog inhibitors of the DNMTs, alone (95) and in combination with HDAC inhibitors (95–98). …
Effects of ionizing radiation on DNA methylation: from experimental biology to clinical applications
IR Miousse, KR Kutanzi, I Koturbash - International journal of …, 2017 - Taylor & Francis
… elements and gene-specific DNA methylation in light of … DNA methylation and discuss ways
in which that understanding can be applied clinically, including utilization of DNA methylation …
in which that understanding can be applied clinically, including utilization of DNA methylation …
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