[HTML][HTML] Translating RNA sequencing into clinical diagnostics: opportunities and challenges

SA Byron, KR Van Keuren-Jensen… - Nature Reviews …, 2016 - nature.com
… Here we review a selection of current and potential clinical applications of RNA-seq, focusing
on differential expression, rare or fusion transcript detection and allele-specific expression, …

[HTML][HTML] RNA-Seq perspectives to improve clinical diagnosis

G Marco-Puche, S Lois, J Benítez, JC Trivino - Frontiers in genetics, 2019 - frontiersin.org
… cover RNA-seq analyses best practices applied to clinical … on how the application of RNA
sequencing (RNA-seq) can … (VUS) identified through DNA sequencing studies such as WES …

[HTML][HTML] Changing technologies of RNA sequencing and their applications in clinical oncology

Y Wang, M Mashock, Z Tong, X Mu, H Chen… - Frontiers in …, 2020 - frontiersin.org
… , and clinical applications in cancer. We will help cancer researchers to understand the
key differences of these RNAseq technologies and their optimal applications. Bulk RNAseq

RNA sequencing role and application in clinical diagnostic

F Peymani, A Farzeen, H Prokisch - Pediatric Investigation, 2022 - mednexus.org
… whole-exome sequencing and whole-genome sequencing has … urged scientists to implement
RNA sequencing (RNA-seq) in the … RNA-seq data can be used to identify aberrantly spliced …

RNA sequencing (RNA-Seq) and its application in ovarian cancer

J Wang, DC Dean, FJ Hornicek, H Shi, Z Duan - Gynecologic oncology, 2019 - Elsevier
… of RNA-Seq compared to other transcriptomics methods and its recent applications in … with
the clinical data, as the patient in this study had no recurrence 19 months post-surgery. The …

The use of exome capture RNA-seq for highly degraded RNA with application to clinical cancer sequencing

M Cieslik, R Chugh, YM Wu, M Wu, C Brennan… - Genome …, 2015 - genome.cshlp.org
clinical samples, especially when specimens are formalin-fixed. To facilitate the use of RNA
sequencing beyond cell lines and in the clinical … performance on degraded RNA. Capture …

RNA sequencing and its applications in cancer diagnosis and targeted therapy

M Wan, J Wang - North American Journal of Medicine and Science, 2014 - najms.com
… In clinical applications, the OSS codes often require modifications to become user-friendly
and need-tailored, and any fault in the operation must be quickly corrected, which requires …

A practical guide to single-cell RNA-sequencing for biomedical research and clinical applications

A Haque, J Engel, SA Teichmann, T Lönnberg - Genome medicine, 2017 - Springer
… Finally, we believe that several clinical applications will emerge for scRNA-seq in the next
5 or so years. For example, resected tumours might be routinely assessed for the presence of …

RNA sequencing for research and diagnostics in clinical oncology

A Buzdin, M Sorokin, A Garazha, A Glusker… - Seminars in cancer …, 2020 - Elsevier
… The resultant profiles may be compared between normal and cancer samples and were
thought to serve as diagnostic assays for clinical applications [53]. It was shown soon after …

RNA sequencing: new technologies and applications in cancer research

M Hong, S Tao, L Zhang, LT Diao, X Huang… - Journal of hematology & …, 2020 - Springer
… studies on RNA sequencing technology and their applications in cancer … for RNA sequencing
technology in cancer applications are … -specific TCRs for further clinical application [175]. …