… developed for applications in PET … in clinical PET imaging. In keeping with the theme of
this issue of Seminars in Nuclear Medicine, we have concentrated on the use of small molecule …

… clinical translation. Following a discussion of the construction of numerous types of NIR-II
small molecules, their imaging applications … for clinical translation of the NIR-II small molecule. …

… Over the past decade, a large number of small molecules with the … for small molecule-based
bone-regenerative engineering. We also review the preclinical study of small molecules …

… In this review, we highlight the preclinical development of key small molecules that are
now being clinically utilized for PCa imaging, discuss the roles of PSMA-targeted agents in …

… small molecule therapeutics could prevent its degradation during storage and transportation.
Small molecule … While hydrophilic small molecule therapeutics are known to have high …

… , and advance clinical outcomes in patients with cancer, fatty liver, and diabetes. This review
identifies small molecule PXR antagonists described to date, discusses possible molecular …

… of the synthesis and clinical use of typical small-molecule JAK inhibitors in different clinical
stages and offers a bright future for the development of novel small-molecule JAK inhibitors. …

… Recognizing the importance of small-molecules on cancer treatment, this review aims to …
the clinical applications and mechanism of action of the thirteen new small-molecules (…

… clinical trials. This review explores the synthetic approaches and clinical applications of
prototypical small-molecule … approval or are currently undergoing clinical trials, highlighting their …

… , some of which have been approved for their clinical use. Despite their success, challenges
… synthesis and clinical application of representative approved small-molecule PDE inhibitors…