Quo vadis, biomarkers?

M Plebani, B Melichar - Clinical Chemistry and Laboratory Medicine …, 2014 - degruyter.com
… of putative biomarkers, less than 100 biomarkers have been validated for clinical practice …
It has been highlighted that the journey of a new biomarker from the bench to the bedside is …

[HTML][HTML] Micro-RNAs as clinical biomarkers and therapeutic targets in breast cancer: Quo vadis?

GS Christodoulatos, M Dalamaga - World journal of clinical …, 2014 - ncbi.nlm.nih.gov
… It is substantial to discover novel biomarkers with diagnostic, … novel, non-invasive biomarkers
in favor of BC diagnosis and … of miRNAs as valuable biomarkers to predict response to …

Biomarkers in chronic graft-versus-host disease: quo vadis?

D Wolff, H Greinix, SJ Lee, T Gooley… - Bone marrow …, 2018 - nature.com
… Third, heterogeneity in laboratory assays not approved for clinical use could cause significant
variations in biomarker verification trials. For example, CXC chemokine motif ligand 9 (…

Alzheimer Disease, Biomarkers, and Clinical Symptoms—Quo Vadis?—Reply

CR Jack - JAMA neurology, 2020 - jamanetwork.com
… 3 biomarker-defined entities with 3 clinical syndromes commonly associated with AD: clinically
… We found that the prevalence of biological AD (defined by the A+T+ biomarker profile) is …

Quo Vadis, molecular imaging?

J Grimm, F Kiessling, BJ Pichler - Journal of Nuclear Medicine, 2020 - Soc Nuclear Med
… Good clinical manufacturing processes need to be established for a swift clinical translation.
… Although MI improves diagnosis by assessing one or a few key biomarkers of a certain …

Alzheimer Disease, Biomarkers, and Clinical Symptoms—Quo Vadis?

M Montero-Odasso, Z Ismail, R Camicioli - JAMA neurology, 2020 - jamanetwork.com
clinical manifestations: mild cognitive impairment, dementia, and probable AD. 1 Notably, this
asymptomatic prevalence of brain load biomarker … and pathological biomarkers to achieve …

Quo vadis: Advanced prostate cancer—clinical care and clinical research in the era of multiple androgen receptor‐directed therapies

W Kim, CJ Ryan - Cancer, 2015 - Wiley Online Library
… The incorporation of surrogate biomarkers into current clinical … and clinical validation (as
well as clinical utility) of candidate surrogates,72 and, finally, integration into prospective clinical

Toward the harmonization of immune monitoring in clinical trials: quo vadis?

CM Britten, S Janetzki, SH Van Der Burg… - Cancer Immunology …, 2008 - Springer
clinical trials but no reliable biomarkers to predict clinical benefit currently exist. For some
cancer types, biomarkers … may act as natural biomarkers for clinical efficiency if the right factors …

Quo Vadis?

Q Vadis - 2011 - academic.oup.com
… and clinically useful after immersing themselves in studying the association between genes
and clinical … More importantly, robustness is essential for any clinical test. It is better to use a …

Hypertension and OMICS, quo vadis

DA Duprez, DR Jacobs Jr - Journal of hypertension, 2024 - journals.lww.com
… was compared with peptide biomarkers of chronic … clinical impacts include new clinical
measures that derive from omics research but that do not involve omics measures in the clinical