… subsequent growth in cases of leptomeningeal metastases. … of clinically relevant mutations
in the brain metastases that … introduction of the idea that brain metastases may not share the …

… Brain metastases are a common complication in cancer patients and an increasingly …
in the United States there are between 97,800 and 170,000 new cases of brain metastases [2•,6,8]. …

… In about 15% of the cases brain abscesses are cryptogenic, and in patients without identified
infectious source, inflammatory laboratory changes are subtle or even absent, making the …

… , clinical features, treatment, and prognosis of brain metastases from systemic malignancies.
… Of the 2375 cases that included an autopsy of the brain, approximately one in four (572, 24…

… brain metastases should be individualized for each patient: in case of single brain metastasis…
options of treatment; in case of multiple lesions, whole-brain radiotherapy is the standard of …

… Although in many cases brain metastases develop in patients with known cancer, often they
originate from an unknown primary tumor which may not be found even at autopsy [24, 25]. …

… In a prospective trial of 48 patients with synchronous clinically silent brain metastases randomized
… Case reports have also shown promising results for the BRAF inhibitor vemurafenib in …

… This case highlights the need to … brain metastases on diagnosis of lung adenocarcinoma.
(A) T1 postcontrast magnetic resonance imaging (MRI) demonstrating two brain metastases. …

… Single metastasis, with an incidence of approximately 14 cases per 100,000 population per
year, and accounts for approximately one-third to one-quarter of these tumors.32,33 As high-…

… Brain metastases (BMs), which are found in approximately 20% of cases at diagnosis and
40% of cases at autopsy in patients with NSCLC, result in significant morbidity and mortality.…