[HTML][HTML] Omega-3 fatty acids and depression: from cellular mechanisms to clinical care

MP Freeman, MH Rapaport - The Journal of clinical psychiatry, 2011 - psychiatrist.com
… omega-3 fatty acids with a lower risk of major depression, perinatal depression, and bipolar
… of individual subjects receiving omega-3 fatty acid supplementation is likely to affect or even …

Meta-analysis of the effects of eicosapentaenoic acid (EPA) in clinical trials in depression

ME Sublette, SP Ellis, AL Geant… - The Journal of clinical …, 2011 - psychiatrist.com
… Objective: Randomized trials of omega-3 polyunsaturated fatty acid (PUFA) treatment for
depression have differed in outcome. Recent meta-analyses ascribe discrepancies to …

Role of omega-3 fatty acids in the treatment of depressive disorders: a comprehensive meta-analysis of randomized clinical trials

G Grosso, A Pajak, S Marventano, S Castellano… - PloS one, 2014 - journals.plos.org
… about the overall clinical efficacy of omega-3 fatty acids (particularly EPA and DHA) in previous
and more recent RCTs published in the last years, minimizing, from a clinical point of view…

The role of polyunsaturated fatty acids in the neurobiology of major depressive disorder and suicide risk

ME Sublette, FM Daray, L Ganança, SR Shaikh - Molecular psychiatry, 2024 - nature.com
fatty acids (LC-PUFAs) are obtained from diet or derived from essential shorter-chain fatty
acids, … There are very few studies of DHA alone in a clinically depressed sample. Of the few …

A meta-analytic review of polyunsaturated fatty acid compositions in patients with depression

PY Lin, SY Huang, KP Su - Biological psychiatry, 2010 - Elsevier
… Consistent with the theoretical relevance and findings from epidemiologic data and clinical
trials, the abnormal fatty acid compositions in cell membranes in patients with mood disorders …

… of omega-3 fatty acids supplementation on depressive symptoms and on health-related quality of life in the treatment of elderly women with depression: a double-blind …

M Rondanelli, A Giacosa, A Opizzi… - Journal of the …, 2010 - Taylor & Francis
fatty acid status reflects the usual dietary intake. Moreover, phospholipids are a model of
fatty acid … in depressed elderly patients appears of relevant clinical importance because …

Essential fatty acids and psychiatric disorders

MM Perica, I Delaš - Nutrition in Clinical Practice, 2011 - Wiley Online Library
… ω-3 fatty acid levels are reduced in depressed patients who … low ω-3 fatty acid levels are
associated with severe depressive … in ω-3, but not ω-6 fatty acids, in MDD and related disorders. …

[HTML][HTML] Dietary intake of n− 3 and n− 6 fatty acids and the risk of clinical depression in women: a 10-y prospective follow-up study

M Lucas, F Mirzaei, EJ O'Reilly, A Pan… - … journal of clinical …, 2011 - Elsevier
depression were documented. Intake of long-chain n−3 fatty acids from fish was not associated
with depression … linolenic acid (ALA) intake was inversely associated with depression risk …

Do essential fatty acids have a role in the treatment of depression?

A Williams, D Katz, A Ali, C Girard, J Goodman… - Journal of affective …, 2006 - Elsevier
… There is substantial evidence supporting the correlation between low essential fatty acid
levels and depression, though clinical trials are scant. As seen with research in other …

Omega-3 fatty acids for major depressive disorder with high inflammation: a randomized dose-finding clinical trial

D Mischoulon, BW Dunlop, B Kinkead… - … Journal of Clinical …, 2022 - psychiatrist.com
Objective: This study compared the impact of 3 eicosapentaenoic acid (EPA) doses versus
placebo on inflammatory biomarkers and depressive symptoms. Methods: Sixty-one …