Machine learning and clinical epigenetics: a review of challenges for diagnosis and classification

S Rauschert, K Raubenheimer, PE Melton… - Clinical epigenetics, 2020 - Springer
… overview of epigenetics and the potential of ML in clinical applications. The interested reader
may refer to the cited literature on the different topics of epigenetics and machine learning. …

Machine learning for epigenetics and future medical applications

LB Holder, MM Haque, MK Skinner - Epigenetics, 2017 - Taylor & Francis
… of molecular epigenetic data in advanced machine learning … selection, and machine learning
on epigenetic data sets is … Active Learning (ACL) to address the expense of generating …

Machine learning in epigenetic diseases

KG Robinson, RE Akins - Medical Epigenetics, 2021 - Elsevier
Epigenetic classifiers can be used in combination with current tools to … epigenetic biomarkers
are currently used clinically. Applications of machine learning in clinical epigenetics hold …

Epigenetic machine learning: utilizing DNA methylation patterns to predict spastic cerebral palsy

EL Crowgey, AG Marsh, KG Robinson, SK Yeager… - BMC …, 2018 - Springer
… The aim of this study was to evaluate epigenetic profiles as biomarkers for spastic CP. A
novel analysis pipeline was employed to assess DNA methylation patterns between peripheral …

The Potential for Artificial Intelligence Applied to Epigenetics

M Vinciguerra - Mayo Clinic Proceedings: Digital Health, 2023 - mcpdigitalhealth.org
… Although AI is a broad concept, machine learning (ML) is the application of AI into a
system or machine, which helps it to self-learn and improve continually. Machine learning

Machine learning approach yields epigenetic biomarkers of food allergy: a novel 13-gene signature to diagnose clinical reactivity

A Alag - PLoS One, 2019 - journals.plos.org
… -computational machine learning approach, conducted using DNA Methylation (DNAm) data,
to accurately diagnose food allergies and potentially find epigenetic targets for the disease. …

Machine learning-based epigenetic classifiers for axillary staging of patients with ER-positive early-stage breast cancer

JIJ Orozco, J Le, M Ensenyat-Mendez, JL Baker… - Annals of surgical …, 2022 - Springer
… Therefore, applying machine-learning methods to epigenetic and clinicopathological data
… for routine clinical practice. In this study, we constructed a machine learning classifier based …

Epigenetics analysis and integrated analysis of multiomics data, including epigenetic data, using artificial intelligence in the era of precision medicine

R Hamamoto, M Komatsu, K Takasawa, K Asada… - Biomolecules, 2019 - mdpi.com
… the advantages of machine learning and deep learning technologies for analysis of medical
… , but a number of machine learning and deep learning technologies possess all four features…

Machine learning in epigenomics: Insights into cancer biology and medicine

E Arslan, J Schulz, K Rai - Biochimica et Biophysica Acta (BBA)-Reviews …, 2021 - Elsevier
Machine learning applications have played crucial roles in addressing multiple questions
related to the basic biology of epigenetic elements, their role in gene regulation, and the utility …

A deep learning model for early risk prediction of heart failure with preserved ejection fraction by DNA methylation profiles combined with clinical features

X Zhao, Y Sui, X Ruan, X Wang, K He, W Dong, H Qu… - … epigenetics, 2022 - Springer
… outperformed models with clinical characteristics or DNA methylation levels alone, published
chronic heart failure risk prediction models and other benchmark machine learning models. …