Upstream therapies for management of atrial fibrillation: review of clinical evidence and implications for European Society of Cardiology guidelines. Part I: primary …

I Savelieva, N Kakouros, A Kourliouros, AJ Camm - Europace, 2011 - academic.oup.com
Atrial fibrillation (AF) is associated with significant morbidity and mortality. It is also a progressive
disease secondary to continuous structural remodelling of the atria due to AF itself, to …

Atrial fibrillation: epidemiology, pathophysiology, and clinical outcomes

L Staerk, JA Sherer, D Ko, EJ Benjamin… - Circulation …, 2017 - Am Heart Assoc
… growth in knowledge and advances in the clinical treatment of atrial fibrillation (AF). It is
now known that AF genesis requires a vulnerable atrial substrate and that the formation and …

Hypertension and atrial fibrillation: doubts and certainties from basic and clinical studies

P Verdecchia, F Angeli, G Reboldi - Circulation Research, 2018 - Am Heart Assoc
… Potential mechanisms by which the renin–angiotensin–aldosterone system may be involved
in the onset of atrial fibrillation. Ang II indicates angiotensin II; and AT 1 , angiotensin II type I…

Role of angiotensin system and effects of its inhibition in atrial fibrillation: clinical and experimental evidence

JR Ehrlich, SH Hohnloser, S Nattel - European heart journal, 2006 - academic.oup.com
… As previous reviews have summarized clinical evidence of anti-AF efficacy of ACE-inhibitors
and ARBs, the present article updates clinical evidence and attempts to elucidate …

Diet and risk of atrial fibrillation–epidemiologic and clinical evidence

NN Gronroos, A Alonso - Circulation Journal, 2010 - jstage.jst.go.jp
… We review the epidemiologic evidence linking diet with the risk of AF and summarize the
potential … Dietary factors might affect the risk of atrial fibrillation (AF), but available studies have …

Novel anticoagulants for stroke prevention in atrial fibrillation: current clinical evidence and future developments

SH Schirmer, M Baumhäkel, HR Neuberger… - Journal of the American …, 2010 - jacc.org
Atrial fibrillation (AF) is the most common cardiac rhythm disorder and a major risk factor for
ischemic stroke. Antithrombotic therapy using aspirin or vitamin K antagonists (VKA) is …

Hypercoagulability, D-dimer and atrial fibrillation: an overview of biological and clinical evidence

E Danese, M Montagnana, G Cervellin… - Annals of Medicine, 2014 - Taylor & Francis
… The onset of subclinical atrial tachyarrhythmias was associated with a significantly increased
risk of clinical atrial fibrillation (HR 5.6; 95% CI 3.8–8.2) and especially of ischemic stroke or …

Atrial fibrillation prevention: an appraisal of current evidence

G Boriani, M Proietti - Heart, 2018 - heart.bmj.com
Atrial fibrillation (AF), which is the most diagnosed arrhythmia, … of AF, along with a strong
clinical evidence of a dose–effect … burden of atrial fibrillation: a challenge for clinicians and …

Mechanisms of atrial fibrillation

RS Wijesurendra, B Casadei - Heart, 2019 - heart.bmj.com
… underlying atrial cardiomyopathy without clinical evidence of … Ablation of Atrial Fibrillation)
trial demonstrated that atrial late … arrhythmia after catheter ablation of AF.37 Thus, increasing …

Epidemiology and natural history of atrial fibrillation: clinical implications

SS Chugh, JL Blackshear, WK Shen… - Journal of the American …, 2001 - jacc.org
… 21st century, atrial fibrillation (AF), an “old” arrhythmia that was … Atrial fibrillation currently
affects approximately 2.2 million … with a primary diagnosis of an arrhythmia (5). The median age …