… and molecular mechanism of tumor angiogenesis, and we will focus on the clinical impact
of recently developed antiangiogenic therapies. Mechanisms of angiogenesis in cancer …

… potent angiogenic factors, has been approved for clinical use in colorectal cancer patients
after a clinical … The clinical implications of angiogenesis in cancer are reviewed in this article. …

… and clinical significance in human cancers, and thus will be the main focuses of this review.
A number of other growth factors or cytokines have been shown to stimulate angiogenesis, …

… angiogenic switch. In this review, we recapitulate the molecular mechanisms involved in this
angiogenic … could lead to development of an angiogenesisbased panel of circulating blood …

… Therefore, the regulators and clinical implications of angiogenesis need to be revisited.
In this review, we discuss recently identified angiogenesis mediators and pathways, new …

… , clinical outcomes are far from satisfying for pancreatic cancer patients receiving anti-angiogenic …
In this review, we summarize the current status of angiogenesis in pancreatic cancer …

… This review highlights the key clinical trial data with … Recent reviews documenting the biology
underpinning the angiogenic … of anti-angiogenic agents are in various stages of clinical trial …

… 1 (VEGFR1) in angiogenesis is still vague. Most cancers exhibit a high expression of VEGF
[8]. … evidence that angiogenesis also plays a central role in breast cancer carcinogenesis and …

… metastases in several pre-clinical minimal disease models; … cancers when they are small,
rather than large, in volume. As such, the most successful clinical application of angiogenesis …

… of angiogenesis during early development and in pathological conditions such as cancer. …
, and also endogenous angiogenic inhibitors to tumor angiogenesis, is beginning to emerge…