Clinical results of vaccine therapy for cancer: learning from history for improving the future

A Choudhury, S Mosolits, P Kokhaei, L Hansson… - Advances in cancer …, 2006 - Elsevier
… relationship between immune and clinical responses to establish whether immune monitoring
could be a reliable surrogate marker for evaluating the clinical efficacy of cancer vaccines. …

Exploring essential issues for improving therapeutic cancer vaccine trial design

CN Baxevanis, SP Fortis, A Ardavanis, SA Perez - Cancers, 2020 - mdpi.com
cancer immunotherapy. Herein, we critically examine important issues for improving cancer
vaccination … We highlight the importance of proper clinical design in terms of selected groups …

Strategies for cancer vaccine development

M Vergati, C Intrivici, NY Huen… - BioMed research …, 2010 - Wiley Online Library
vaccine platforms should be a concern of cancer vaccine clinical trials, along with clinical
employed by recent clinical trials of therapeutic cancer vaccines and analyzes them both …

[HTML][HTML] Correlates of immune and clinical activity of novel cancer vaccines

SH van der Burg - Seminars in Immunology, 2018 - Elsevier
… tumors and metastases after vaccination or reflect a stronger clinical impact of vaccine in a
… which vaccine-induced tumor immunity correlates with the clinical impact of cancer vaccines

Self-adjuvanting lipoimmunogens for therapeutic HPV vaccine development: potential clinical impact

KY Shen, LS Chang, CH Leng, SJ Liu - Expert Review of Vaccines, 2015 - Taylor & Francis
cancer; however, in this report, we focus on the development of subunit vaccines for the
treatment of HPV-associated cancer. … a cancer vaccine adjuvant was evaluated in clinical trials of …

Therapeutic cancer vaccine: building the future from lessons of the past

T Tran, C Blanc, C Granier, A Saldmann… - Seminars in …, 2019 - Springer
… antigens as novel targets for vaccine foster new clinical development of cancer vaccines [3]. …
cancer vaccine has been shown to induce specific CD8 + T cells but with no clinical impact […

Personalized cancer vaccines: clinical landscape, challenges, and opportunities

CS Shemesh, JC Hsu, I Hosseini, BQ Shen, A Rotte… - Molecular Therapy, 2021 - cell.com
… Therapeutic cancer vaccines (TCVs) are attractive systemic … Our review highlights key
issues impacting TCVs in clinical … , obstacles, and regulation of cancer vaccines. Most trials of …

Cancer vaccine adjuvants–recent clinical progress and future perspectives

AH Banday, S Jeelani, VJ Hruby - Immunopharmacology and …, 2015 - Taylor & Francis
… provides an overview of latest advancements in adjuvant and cancer vaccine technologies,
the current clinical status of various adjuvants and their application to cancer vaccines. …

Therapeutic vaccines for cancer: an overview of clinical trials

I Melero, G Gaudernack, W Gerritsen, C Huber… - Nature reviews Clinical …, 2014 - nature.com
… This Review provides an overview of new results from clinical studies of therapeutic cancer
vaccines directed against tumour-associated antigens and discusses their implications for …

[HTML][HTML] A comparison of cancer vaccine adjuvants in clinical trials

M Marriott, B Post, L Chablani - Cancer Treatment and Research …, 2023 - Elsevier
… Most of our learning about vaccines and … cancer vaccines. This review will focus on
FDA-approved and experimental adjuvants being evaluated for therapeutic cancer vaccines and …