… Although the injection of human cancer cells into immunocompromised mice has aided our
understanding of the role of HIFs in cancer, this approach exclusively evaluates the terminal …

Background Data on patients with COVID-19 who have cancer are lacking. Here we characterise
the outcomes of a cohort of patients with cancer and COVID-19 and identify potential …

It is almost 50 years since antimetabolites were first found to have clinical antitumour activity,
with Farber's discovery that aminopterin could cause remission in acute leukaemia. In the …

… that render complete cancer genome characterization … and clinical insights gleaned from
systematic cancer genome characterization. We also discuss how the convergence of cancer …

… fusions in human cancers remains … the clinical impact of large-scale prospective tumor
sequencing, more systematic studies are needed to assess the long-term effects of clinical cancer …

… patterns in specific cancers and to investigate the functional and clinical impact of mutations…
reported in human cancers and populations, with annotations related to the clinical and …

… In this study performed in vitro in human colon cancer cells, sensitisation to 5-fluorouracil,
paclitaxel and etoposide has been obtained. All these preclinical evidences underline the …

… of hTERT is believed to play a major role in telomerase activation in human cancers. … not
hTERT rearrangements are used by different types of cancers, and as well their clinical impact. …

… Because CD8 + , DC-LAMP + , and NKp46 + cell densities in lung metastases have different
clinical impacts in colorectal carcinoma and RCC, we compared their microenvironments. …

… Antiangiogenic cancer treatment is still largely experimental and its clinical potential is currently
being studied in clinical … strategy for treating human cancer has recently been published. …