Brain–gut axis: clinical implications

J Khlevner, Y Park, KG Margolis - Gastroenterology Clinics, 2018 - gastro.theclinics.com
The importance of the gastrointestinal (GI) tract in human disease was first raised by
Hippocrates m more than 2000 years ago. His statement, that “all disease begins in the gut,” …

The gut–brain axis and the microbiome: mechanisms and clinical implications

V Osadchiy, CR Martin, EA Mayer - Clinical Gastroenterology and …, 2019 - Elsevier
Background & Aims Based largely on results from preclinical studies, the concept of a brain
gut microbiome axis has been established, mediating bidirectional communication between …

Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities

MA Ortega, MA Álvarez-Mon, C García-Montero… - Molecular …, 2023 - nature.com
Bipolar disorders (BD) represent a severe leading disabling mental condition worldwide
characterized by episodic and often progressive mood fluctuations with manic and depressive …

Principles and clinical implications of the brain–gut–enteric microbiota axis

SH Rhee, C Pothoulakis, EA Mayer - Nature reviews Gastroenterology & …, 2009 - nature.com
While bidirectional brain–gut interactions are well known mechanisms for the regulation of
gut function in both healthy and diseased states, a role of the enteric flora—including both …

Adrenal disorders and the paediatric brain: pathophysiological considerations and clinical implications

V Salpietro, A Polizzi, G Di Rosa… - International journal …, 2014 - Wiley Online Library
… -brain axis in the regulation of CSF pressure homeostasis. Arterial hypertension caused by
paediatric adenomas or tumours of the adrenal cortex or medulla has been associated with …

[HTML][HTML] Psychoneuroimmunoendocrinology: clinical implications

SN González-Díaz, A Arias-Cruz… - World Allergy …, 2017 - Elsevier
… Major clinical implications and a vast amount of pathologies are related to the relationships
… This review seeks to gather knowledge and the main clinical implications from the field of …

Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS

L Liu, JR Huh, K Shah - EBioMedicine, 2022 - thelancet.com
… The microbiota-gut-brain axis The signaling mechanism behind the microbiota-gut-brain
axis communication is of particular interest when considering therapeutic design. The brain

The microbiota-gut-brain axis in health and disease and its implications for translational research

MA Schächtle, SP Rosshart - Frontiers in cellular neuroscience, 2021 - frontiersin.org
… This development also led to the discovery of the gut-brain axis as the crucial … brain physiology.
Moreover, it became evident that the communication along this microbiota-gut-brain axis

Brain–heart interactions: physiology and clinical implications

A Silvani, G Calandra-Buonaura… - … of the Royal …, 2016 - royalsocietypublishing.org
… Given these clinical implications, in the present section we will characterize the clinical
features, the supposed pathogenetic mechanisms, and the common causes of autonomic …

Interactions between the hypothalamic-pituitary-adrenal axis and the female reproductive system: clinical implications

GP Chrousos, DJ Torpy, PW Gold - Annals of internal medicine, 1998 - acpjournals.org
… The clinical implications of placental CRH extend beyond pregnancy, labor, and delivery [76,
77] (Figure 5 and Figure 6). The postpartum period is characterized by an increased …