Antiviral drug resistance: mechanisms and clinical implications
L Strasfeld, S Chou - Infectious Disease Clinics, 2010 - id.theclinics.com
… Prolonged antiviral drug exposure and ongoing … drug resistance, which may manifest as
persistent or increasing viremia or disease despite therapy. Consequences of drug resistance …
persistent or increasing viremia or disease despite therapy. Consequences of drug resistance …
EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
T Shibue, RA Weinberg - Nature reviews Clinical oncology, 2017 - nature.com
… limited by the development of drug resistance. Such acquired resistance is driven, in part, …
a possible mechanistic basis for anticancer drug resistance. In fact, accumulating evidence …
a possible mechanistic basis for anticancer drug resistance. In fact, accumulating evidence …
Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a TBNET/RESIST-TB consensus statement
J Domínguez, EC Boettger, D Cirillo… - … of tuberculosis and …, 2016 - ingentaconnect.com
… tuberculosis has implications for the … detecting resistance-associated mutations in drugs
for which there is poor or unproven correlation between phenotypic and clinical drug resistance …
for which there is poor or unproven correlation between phenotypic and clinical drug resistance …
Clinical implications of the phenomenon of drug resistance
JH Goldie, AJ Coldman - Drug and hormone resistance in …, 2019 - taylorfrancis.com
… ratio between drug sensitive and drug resistant cells. If the proportion of drug resistant cells
is quite low and if the treatment given falls well short of eradicating all of the drug sensitive …
is quite low and if the treatment given falls well short of eradicating all of the drug sensitive …
Clinical implications of drug resistance
HMW Verheul, HM Pinedo - Cambridge University Press …, 1998 - books.google.com
1. Tumor types in which a large fraction of patients can be cured. Here we should differentiate
between those patients with advanced disease and those treated in an adj uvant setting …
between those patients with advanced disease and those treated in an adj uvant setting …
Cytomegalovirus drug resistance and clinical implications
SW Chou - Transplant Infectious Disease, 2001 - Wiley Online Library
… isolates often contain multiple resistance mutations. A limitation of genotypic assays is that
… drug resistance and risk factors Much of our existing knowledge about CMV drug resistance …
… drug resistance and risk factors Much of our existing knowledge about CMV drug resistance …
Antiretroviral drug resistance testing in adults with HIV infection: implications for clinical management
MS Hirsch, B Conway, TD Richard, VA Johnson… - Jama, 1998 - jamanetwork.com
… The italicized letter below the residue indicates the substitution that confers drug resistance.
The drug-… To review current knowledge of the biology and clinical implications of human …
The drug-… To review current knowledge of the biology and clinical implications of human …
Molecular mechanisms and clinical implications of miRNAs in drug resistance of colorectal cancer
L Duan, W Yang, W Feng, L Cao… - Therapeutic …, 2020 - journals.sagepub.com
… drug resistance in CRC. Certain of these miRNAs may thus be used as promising biomarkers
for predicting drug … We also discuss the potential role of drug resistance-related miRNAs as …
for predicting drug … We also discuss the potential role of drug resistance-related miRNAs as …
Antiplatelet drug resistance: Molecular insights and clinical implications
… that are known to confer resistance. Here we present molecular insights into the mechanisms
for aspirin and clopidogrel resistance, with a discussion of their clinical implications. …
for aspirin and clopidogrel resistance, with a discussion of their clinical implications. …
Clinical implications of multi-drug resistance in the intensive care unit
DR Snydman - Scand J Infect Dis, 1991 - Taylor & Francis
… However, the frequency of cross-resistance and the development of resistance to fJ-lactams …
, many clinicians are not generally aware of the clinical implications of cross-resistance. Addi…
, many clinicians are not generally aware of the clinical implications of cross-resistance. Addi…
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