… Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family:
molecular mechanism and clinical implications for endocrine therapy resistance. Endocr Rev 2008…

… However, many clinical studies revealed the emergence of drug-resistant mutants during …
HBV drug-resistant mutant selection and on the clinical implications of HBV drug resistance for …

… The main clinical implications involve early detection of imatinib resistance and the …
tool used to predict, clinically detect, and treat targeted drug resistance. This need arises …

… pathogenic mechanisms leading to BC and provide the state of the art on RET targeted
inhibitors as therapeutic drugs, combined to overcome drug resistance in selected BC patients. …

… Drug resistance still remains a major cause of treatment failure and death in acute … So-called
classic multi-drug resistance (MDR) is related to the overexpression of a 170 kd …

… With the approval in 2007 of the first integrase inhibitor (INI), raltegravir, clinicians became
… of the most highly drug-resistant viruses. Raltegravir also provided clinicians with additional …

… mechanisms of drug resistance and their genetic dissemination. Resistance takes many
forms and is often a complex process, as in the case of multidrug resistance. However, the …

… In the phase I study, clinical activity was reported in trastuzumab-resistant breast cancer
patients [97]. A phase II trial of lapitinib in heavily pretreated patients with advanced breast …

… The prevalence of drug resistance among persons with … associated with genotypic drug
resistance were analyzed … Terry Beirn Community Programs for Clinical Research on Acquired …

… This review gives an overview on the various clinical studies that have investigated the
prevalence and clinical importance of laboratory aspirin resistance. Moreover, therapeutic options…