Molecular biology of lung cancer: clinical implications

JE Larsen, JD Minna - Clinics in chest medicine, 2011 - chestmed.theclinics.com
… to the biological behavior of lung cancer, and their utility … lung cancer pathogenesis and
their timing in preneoplasia, primary cancer, and metastatic disease and the clinical implications

Molecular biology of lung cancer: clinical implications

KM Fong, JD Minna - Clinics in chest medicine, 2002 - chestmed.theclinics.com
… of molecular and biologic changes in lung cancer cells. This review … lung cancer pathogenesis
to clinical practice. The challenge is to translate discoveries regarding how lung cancers

Lung cancer• 9: Molecular biology of lung cancer: clinical implications

KM Fong, Y Sekido, AF Gazdar, JD Minna - Thorax, 2003 - thorax.bmj.com
lung cancer cells during their pathogenesis. , 6 Much more is known about the molecular
abnormalities that occur in clinically overt lung cancers… of genes in individual lung cancers, with …

[HTML][HTML] Molecular heterogeneity in lung cancer: from mechanisms of origin to clinical implications

FZ Marino, R Bianco, M Accardo, A Ronchi… - … journal of medical …, 2019 - ncbi.nlm.nih.gov
… mechanisms underlying molecular heterogeneity in lung cancer, including epigenetic
mechanisms, … molecular heterogeneity involved in therapeutic implications in lung cancer patients. …

Mutations of the Epidermal Growth Factor Receptor Gene in Lung Cancer: Biological and Clinical Implications

T Kosaka, Y Yatabe, H Endoh, H Kuwano, T Takahashi… - Cancer research, 2004 - AACR
… To gain further insights in the role of EGFR in lung carcinogenesis, we sequenced exons
18… with lung cancer who underwent surgical resection and correlated the results with clinical

Aberrant DNA methylation in lung cancer: biological and clinical implications

S Zöchbauer-Müller, JD Minna, AF Gazdar - The oncologist, 2002 - academic.oup.com
cancer-related genes in lung cancer, occurs already in smoking-damaged bronchial epithelium
from cancer-free … agents, and may be a useful biomarker for lung cancer risk assessment. …

Molecular pathologic substaging in 244 stage I non-small-cell lung cancer patients: clinical implications.

DJ Kwiatkowski, DH Harpole Jr, J Godleski… - Journal of clinical …, 1998 - ascopubs.org
… I disease (tumor confined to the lung without distant metastases or positive lymph nodes). …
-cell lung cancer (NSCLC) and has the best prognosis.Nonetheless, the cancer relapse and …

[HTML][HTML] CircRNAs in lung cancer-Biogenesis, function and clinical implication

C Wang, S Tan, J Li, WR Liu, Y Peng, W Li - Cancer letters, 2020 - Elsevier
… Molecular mechanisms underlying tumorigenesis and development of lung cancer are …
cancers. However, the expression patterns and clinical implications of circRNAs in lung cancer

Clinical implication and prognostic significance of standardised uptake value of primary non-small cell lung cancer on positron emission tomography: analysis of 176 …

N Al-Sarraf, K Gately, J Lucey, R Aziz… - European journal of …, 2008 - academic.oup.com
… Objective: We sought to assess the clinical implication and prognostic significance of
maximum standardised uptake value (SUV max ) of primary non-small cell lung cancer (NSCLC) …

[HTML][HTML] Genetic and epigenetic changes in lung carcinoma and their clinical implications

J Wen, J Fu, W Zhang, M Guo - Modern Pathology, 2011 - Elsevier
… In this review, we summarize the characteristic genetic and epigenetic changes observed
in lung cancers and the implication of these changes in patients for early detection, survival …