Genetics of systemic lupus erythematosus: clinical implications

KE Sullivan - Rheumatic Disease Clinics of North America, 2000 - Elsevier
Systemic lupus erythematosus (SLE) is the prototypic systemic autoimmune disease. The
clinical features are well-known: production of autoantibodies, immune complex–mediated end…

[HTML][HTML] Apoptosis in systemic lupus erythematosus: clinical implications

F Andrade, L Casciola-Rosen, A Rosen - Rheumatic Disease Clinics of …, 2000 - Elsevier
Systemic lupus erythematosus (SLE) is a heterogeneous and complex group of disorders of
unclear cause. The complexity arises from three major sources (genes, environment, and …

Redefining lupus nephritis: clinical implications of pathophysiologic subtypes

F Yu, M Haas, R Glassock, MH Zhao - Nature Reviews Nephrology, 2017 - nature.com
… The main purposes of renal biopsy in patients with systemic lupus erythematosus are to
confirm the diagnosis of lupus nephritis, to assess disease activity and/or chronicity, guide …

Thrombocytopenia in patients with systemic lupus erythematosus: significant in the clinical implication and prognosis

H Zhao, S Li, R Yang - Platelets, 2010 - Taylor & Francis
… to determine the characteristics of the clinical manifestations, laboratory findings and
prognostic impact of the thrombocytopenia patients with systemic lupus erythematosus (SLE). The …

Clinical implications of neuropsychiatric systemic lupus erythematosus

A Mak, RCM Ho, CS Lau - Advances in psychiatric treatment, 2009 - cambridge.org
… Systemic lupus erythematosus (SLE) is an auto immune disorder mediated by the
immune complex and characterised by its protean clinical mani festation and multisystemic …

Lupus thrombocytopenia: clinical implications and prognostic significance

PD Ziakas, S Giannouli, E Zintzaras… - Annals of the …, 2005 - ard.bmj.com
… of platelets is a common clinical manifestation in systemic lupus erythematosus (SLE),
ranging … Apart from diverse aetiologies in lupus thrombocytopenia, its clinical implications and …

Clinical implications and prognostic significance of thrombocytopenia in Tunisian patients with systemic lupus erythematosus

M Jallouli, M Frigui, S Marzouk, M Snoussi… - Lupus, 2012 - journals.sagepub.com
… Thrombocytopenia is a common clinical manifestation and one of the hematological criteria
of systemic lupus erythematosus (SLE) according to the American College of Rheumatology (…

B cell activating factor (BAFF): structure, functions, autoimmunity and clinical implications in systemic lupus erythematosus (SLE)

T Möckel, F Basta, J Weinmann-Menke… - Autoimmunity reviews, 2021 - Elsevier
… BAFF overexpression has been commonly detected among patients with Systemic Lupus
Erythematosus (SLE) and seems to be strongly involved in the pathogenesis of the disease. …

Key issues in the management of patients with systemic lupus erythematosus: latest developments and clinical implications

N Jordan, D D'Cruz - Therapeutic Advances in …, 2015 - journals.sagepub.com
… in SLE management, outlining recent developments and clinical implications for patients. …
for lupus disease control and further therapies yet to emerge. The clinical implications of …

Current paradigms of tolerogenic dendritic cells and clinical implications for systemic lupus erythematosus

P Ritprajak, C Kaewraemruaen, N Hirankarn - Cells, 2019 - mdpi.com
… This review also highlights the clinical implications of tolDC-based therapy for SLE treatment,
examines the current clinical therapeutics in patients with SLE, which can generate tolDC …