… , with worse prognoses, than men with prostate cancer without these mutations. This finding
has important clinical implications because carriers diagnosed with prostate cancer could be …

… polymorphisms recurrent throughout the prostate cancer-diagnosed genome. Castration-resistant
prostate cancer is the most aggressive form of prostate cancer, and its research has …

… for development of biomarkers for cancer detection and risk stratification and as … prostate
cancer cells and discuss the potential clinical implications with regards to prostate cancer …

… chemoprevention of prostate cancer to review critically the results of the trial for themselves.
… Disclosures: This manuscript was an outcome of the European Prostate Cancer Forum, …

… Both obesity and prostate cancer (PCa) are epidemic in Western society. Although initial …
an emphasis on the clinical implications and how to improve outcomes among obese men. …

… Prostate cancer is the most frequent nonskin cancer and second most common cause of
cancer-related deaths in man. Prostate cancer is a clinically heterogeneous disease with many …

… , and clinical practice as a whole. We outline a selected number of important genomic
alterations in prostate cancer, and discuss the clinical implications of these discoveries (Table 1). …

… and its relationship to prostate cancer. We further discuss the validation and clinical utility of
PTEN as a prognostic biomarker in localized prostate cancer and consider progress towards …

… and androgens brought about by the saturation model has important clinical implications. …
of androgens and PCa, with important clinical implications. The key conceptual change is that …

… , molecular-targeted therapy for this malignancy has not been extensively studied in the clinic.
We review the genomic landscape of prostate cancer and implications for clinical research …