Clinical implications of antimicrobial resistance for therapy

AP MacGowan - Journal of antimicrobial chemotherapy, 2008 - academic.oup.com
… In the following sections, I will assess the importance of clinical resistance for therapeutic
outcomes in a range of clinical situations: BSI/pneumonia in intensive care unit (ICU) and …

Resistance and escape from antiangiogenesis therapy: clinical implications and future strategies

JN Bottsford-Miller, RL Coleman… - Journal of Clinical …, 2012 - ascopubs.org
… mechanistic complexity, therapeutic resistance and escape … to antiangiogenic therapy,
leading to drug resistance. These … invasive capacity, and intrinsic resistance to hypoxia. The …

Impact of cancer metabolism on therapy resistanceclinical implications

AC Gonçalves, E Richiardone, J Jorge, B Polónia… - Drug Resistance …, 2021 - Elsevier
… as well as targeted therapies. Furthermore, we report the … in therapy resistance and
how adaptations in amino acid, glucose, and lipid metabolism support the growth of therapy-resistant

[PDF][PDF] Therapy: Synthesis of the Literature and Clinical Implications

LG Miller, RD Hays - The AIDS reader, 2000 - researchgate.net
… Adherence to combination antiretroviral therapy has a strong impact on virologic response
and emergence ofviral resistance. However, monitoring adherence in the clinic is difficult. …

Antiviral drug resistance: mechanisms and clinical implications

L Strasfeld, S Chou - Infectious Disease Clinics, 2010 - id.theclinics.com
… Consequences of drug resistance range from … , implications, and management of resistance
to antiviral drugs used to treat several viral infections that play a significant role in the clinical

Clinical implications of resistance to antiretrovirals: new resistance technologies and interpretations

M Mascolini, D Richman, B Larder, J Mellors… - … therapy, 2008 - journals.sagepub.com
… Drug Resistance Workshop gathers leading investigators and resistance-savvy clinicians to
… , epidemiology, and clinical implications of resistance to licensed and experimental antivirals…

Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications

R Leclercq - Clinical infectious diseases, 2002 - academic.oup.com
… is unequal in terms of incidence and of clinical implications. Modification of the ribosomal
target confers broad-spectrum resistance to macrolides and lincosamides, whereas efflux and …

Molecular mechanism and clinical implications of endocrine therapy resistance in breast cancer

G Arpino, C De Angelis, M Giuliano, A Giordano… - Oncology, 2010 - karger.com
… the development of resistance to hormone therapies. The aim … of resistance of breast cancer
cells to endocrine therapies due … to explore newly available therapeutic strategies that could …

Clinical implications of the phenomenon of drug resistance

JH Goldie, AJ Coldman - Drug and hormone resistance in …, 2019 - taylorfrancis.com
… indirect evidence that spontaneous mutations to resistance are occurring in clinical tumors
with the consequent expected variance in resistant subtypes from individual to individual. …

[PDF][PDF] Antimicrobial resistance in Asia: current epidemiology and clinical implications

CI Kang, JH Song - Infection & chemotherapy, 2013 - synapse.koreamed.org
… of resistance and understand the appropriate use of antimicrobial agents in clinical practice.
… and clinical implications of antimicrobial-resistant bacterial infections in Asian countries. …