… Vascular ageing starts early in life and is characterized by a gradual change of vascular …
most important molecular pathways involved in vascular ageing, their association with arterial …

… through the early vascular ageing (EVA) concept, first introduced in 2008 [3] and then further
expanded [4,5] , building on earlier observations that arterial ageing and cardiovascular risk …

… Oxidative stress is critically involved in many of the molecular events of vascular ageing,
including: (1) increased pro-inflammatory responses in vascular cells, (2) vascular dysfunction …

… We review the vascular phenotype in aging and hypertension, focusing on arterial stiffness
and vascular remodelling. We also highlight the clinical implications of these processes and …

… efforts, should reduce the predicted trends in cardiovascular morbidity and mortality among
the aged. … Under resting conditions, the clinical implications would seem insignificant. …

… signs of an unsuccessful vascular ageing. This unsuccessful ageing (accelerated ageing),
if … review key pathophysiologic concepts concerning vascular ageing and associated risk of …

… aging may contribute to design new mechanism-based therapeutic approaches to attenuate
the features of vascular senescence and its clinical impact on the cardiovascular system. …

… specifically on vascular disease states of the elderly, including systolic hypertension,
vascular calcification, and dementia, and we review relevant basic and clinical discoveries that …

A large and growing segment of the general population are age 65 or older, and this percentage
will continue to rise. Primary care of this population has, and is becoming a priority for …

… in vascular ageing due to gonadal function, vascular … may lead to premature arterial vascular
ageing. These include … -invasive vascular ageing measures in routine clinical settings by …