Biomarkers predicting clinical outcome of epidermal growth factor receptor–targeted therapy in metastatic colorectal cancer

S Siena, A Sartore-Bianchi… - Journal of the …, 2009 - academic.oup.com
growth factor receptor (EGFR), a member of the human epidermal growth factor receptor (HER)–erbB
family of receptor … processes involved in tumor growth and progression, including …

Targeting the epidermal growth factor receptor in radiotherapy: radiobiological mechanisms, preclinical and clinical results

M Baumann, M Krause - Radiotherapy and oncology, 2004 - Elsevier
… Inhibition of the epidermal growth factor receptor (EGFR) is a fastly developing field in
preclinical and clinical cancer research. This review presents the current status of knowledge and …

Epidermal growth factor receptor expression in breast cancer association with biologic phenotype and clinical outcomes

MF Rimawi, PB Shetty, HL Weiss… - … Journal of the …, 2010 - Wiley Online Library
… relation between hormone receptor expression and growth factor receptor expression and
… of breast carcinomas and linked them to varying clinical outcomes.42, 43 Basal-type breast …

Epidermal growth factor receptor as a target for chemotherapy

D Vallböhmer, HJ Lenz - Clinical colorectal cancer, 2005 - Elsevier
growth factor receptor monoclonal antibody EMD72000 in patients with advanced solid
tumors that express the epidermal growth factor receptor. J Clin Oncol 2004; 22:175-184. 28. …

Impact of Epidermal Growth Factor Receptor and KRAS Mutations on Clinical Outcomes in Previously Untreated Non–Small Cell Lung Cancer Patients: Results of an …

DM Jackman, VA Miller, LA Cioffredi, BY Yeap… - Clinical Cancer …, 2009 - AACR
… The impact of epidermal growth factor receptor (EGFR) and KRAS mutations on clinical
outcomes … We have created a database of five clinical trials from the United States and Europe, in …

Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer

S Temam, H Kawaguchi, AK El-Naggar… - Journal of Clinical …, 2007 - ascopubs.org
Purpose Overexpression of epidermal growth factor receptor (EGFR) is common in head and
neck squamous cell carcinoma (HNSCC). Recent studies showed that EGFR inhibitors are …

Epidermal growth factor receptor gene copy number and clinical outcome of metastatic colorectal cancer treated with panitumumab

A Sartore-Bianchi, M Moroni, S Veronese… - Journal of Clinical …, 2007 - ascopubs.org
… cancer (mCRC) to anti–epidermal growth factor receptor (EGFR) monoclonal antibodies
has a … role of EGFR GCN, in terms of clinical outcome, in patients treated with panitumumab. …

Epidermal growth factor receptor polymorphisms and clinical outcomes in non-small-cell lung cancer patients treated with gefitinib

G Liu, S Gurubhagavatula, W Zhou, Z Wang… - The …, 2008 - nature.com
… The−216G/T, −191C/A, intron 1 and Arg497Lys epidermal growth factor receptor (EGFR) …
EGFR intron 1 and –216G/T polymorphisms influence clinical outcomes in gefitinib-treated …

Epidermal growth factor receptor expression in high-grade osteosarcomas is associated with a good clinical outcome

C Kersting, C Gebert, K Agelopoulos, H Schmidt… - Clinical cancer …, 2007 - AACR
… of the epidermal growth factor receptor (EGFR) in osteosarcomas has repeatedly been
described. With the introduction of anti-EGFR–targeted therapies in clinical practice, these …

Relationships of insulin-like growth factor-1 receptor and epidermal growth factor receptor expression to clinical outcomes in patients with colorectal cancer

D Takahari, Y Yamada, NT Okita, T Honda… - Oncology, 2008 - karger.com
… the prognostic implications of insulin-like growth factor-1 receptor (IGF-1R), epidermal
growth factor receptor (EGFR) and human epidermal growth factor receptor (HER)-2 in patients …