Clinical outcomes in non‐small‐cell lung cancer patients with EGFR mutations: pooled analysis

L Paz‐Ares, D Soulières, I Melezínek… - Journal of cellular …, 2010 - Wiley Online Library
… ) is a distinct subgroup of NSCLCs that is particularly responsive to EGFR tyrosine… clinical
outcome in patients with EGFR-mutated NSCLC who were treated with chemotherapy or EGFR

Mutations in TP53, PIK3CA, PTEN and other genes in EGFR mutated lung cancers: Correlation with clinical outcomes

PA VanderLaan, D Rangachari, SM Mockus, V Spotlow… - Lung cancer, 2017 - Elsevier
… gene assay analysis for EGFR mutations in NSCLC, which … oncogene mutations may impact
the clinical outcomes of EGFR … can be identified in advanced EGFR mutated NSCLC using …

EGFR mutations and clinical outcomes of chemotherapy for advanced non-small cell lung cancer: a meta-analysis

Q Zhang, HH Dai, HY Dong, CT Sun, Z Yang, JQ Han - Lung Cancer, 2014 - Elsevier
… NSCLC stratified by EGFR mutation status. The … clinical studies have suggested patients
with mutated EGFR have poorer responses to chemotherapy than patients with wild-type EGFR

[HTML][HTML] Uncommon EGFR mutations in non-small-cell lung cancer: A systematic literature review of prevalence and clinical outcomes

T John, A Taylor, H Wang, C Eichinger, C Freeman… - Cancer …, 2022 - Elsevier
… IIIB/IV) NSCLC and the clinical outcomes associated with these mutations. Having identified
… all EGFR mutations represented by uncommon mutations, and to compare clinical outcomes

[HTML][HTML] Beyond disease-progression: Clinical outcomes after EGFR-TKIs in a cohort of EGFR mutated NSCLC patients

RA Tudor, A D'Silva, A Tremblay, P MacEachern… - PLoS …, 2017 - journals.plos.org
EGFR-TKI at the time of disease-progression on PFS [21]. Our study however, assessed the
clinical outcomes … Our findings highlight favourable outcomes in PPS if EGFRmut + NSCLC …

[HTML][HTML] Clinical outcomes of EGFR-TKI treatment and genetic heterogeneity in lung adenocarcinoma patients with EGFR mutations on exons 19 and 21

JY Yu, SF Yu, SH Wang, H Bai, J Zhao, TT An… - Chinese journal of …, 2016 - Springer
… exhibit different responsiveness to EGFR-TKIs and what are the potential mechanism for …
the clinical outcomes of EGFR-TKI treatment in patients with EGFR 19 del and L858R mutations

… growth factor receptor (EGFR) mutations and clinical characteristics on outcomes after treatment with EGFR tyrosine kinase inhibitors versus chemotherapy in EGFR …

CK Lee, YL Wu, PN Ding, SJ Lord, A Inoue… - Journal of Clinical …, 2015 - ascopubs.org
… of EGFR TKIs by EGFR mutation status. The included studies were randomized trials that
compared EGFR … diagnosed advanced NSCLC with sensitizing EGFR mutations. In brief, we …

Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma

EY Kim, EN Cho, HS Park, JY Hong, S Lim… - Cancer biology & …, 2016 - Taylor & Francis
… compound EGFR mutation had properties which might be related to poor clinical outcome, …
survival (OS) of cases with simple and compound mutations ( Fig. 1 ). The median follow-up …

Pooled analysis of clinical outcome for EGFR TKI‐treated patients with EGFR mutation‐positive NSCLC

L Paz‐Ares, D Soulieres, J Moecks… - Journal of Cellular …, 2014 - Wiley Online Library
… This paper describes an updated literature search for clinical studies of erlotinib, gefitinib
and other EGFR TKIs in patients with EGFR mutation-positive NSCLC, and reports the results …

Comparable clinical outcomes in patients with HER2‐mutant and EGFR‐mutant lung adenocarcinomas

CH Gow, HT Chang, CK Lim, CY Liu… - Genes …, 2017 - Wiley Online Library
… We subsequently performed multiple-driver mutation and clinical-characteristic analyses of
… only able to compare clinical outcomes for the 640 patients with HER2 (n = 33), EGFR (n = …