… relatives, and parental reproductive planning and outcomes. Our results show the broader
longer-term effectiveness and cost-effectiveness of genomic sequencing in clinical care. …

… Trio-rapid genome sequencing provided higher … clinical exome sequencing. Precise and
fast molecular diagnosis can alter medical management and positively impact patient outcomes…

… Overall impact of genomic alterations on clinical outcome in lung adenocarcinoma We next
assessed the impact of each genomic alteration on the clinical outcomes of patients in our …

… modality in clinical genetics and in surveys of reportable genetic findings in unselected …
Whole-genome sequencing is expected to provide superior coverage of certain genomic regions, …

… clinical outcomes and the usefulness or added value in decision-making compared with not
using the test.” In the ACCE framework, a series of questions relating to test characteristics, …

… genomics in children and adults because many issues in somatic genomic and prenatal
sequencing … , the first randomized clinical trial to integrate whole-genome sequencing into the …

… of this heterogeneity on clinical outcome. Here, we report comprehensive genomic and …
cancer (mCRPC) linked with longitudinal clinical outcomes, integrating findings from whole-…

… the sequence data to determine which variants may be clinically meaningful. Whole-exome
sequencing is less costly than whole-genome sequencing, … subset of the genome in which to …

… of the genome might also reflect clinical outcome. After … aim to introduce clinical whole-genome
sequencing into real-… ’ targeted therapies and recruitment into clinical trials. However, …

… clinical utility for patients undergoing genetic investigations. However, evidence of clinical …
the literature on the clinical utility of exome/genome sequencing across disease indications in …