Biomarkers predicting clinical outcome of epidermal growth factor receptor–targeted therapy in metastatic colorectal cancer

S Siena, A Sartore-Bianchi… - Journal of the …, 2009 - academic.oup.com
… and cetuximab that target the epidermal growth factor receptor (EGFR) have expanded the
… by immunostaining does not reliably predict clinical outcome of EGFR-targeted treatment has …

Transforming growth factor β1 is associated with angiogenesis, metastasis, and poor clinical outcome in prostate cancer

P Wikström, P Stattin, I Franck‐Lissbrant… - The …, 1998 - Wiley Online Library
BACKGROUND Prostate tumors express high levels of transforming growth factor‐β1 (TGF‐β1)
and seem to acquire resistance to its antiproliferative effects with tumor progression. …

Epidermal growth factor receptor expression in breast cancer association with biologic phenotype and clinical outcomes

MF Rimawi, PB Shetty, HL Weiss… - … Journal of the …, 2010 - Wiley Online Library
… Epidermal growth factor receptor (EGFR) expression is associated with … Clinical and biological
features of EGFR‐positive and EGFR‐negative tumors were compared. Clinical outcomes

Association between HER-2/neu and Vascular Endothelial Growth Factor Expression Predicts Clinical Outcome in Primary Breast Cancer Patients

GE Konecny, YG Meng, M Untch, HJ Wang… - Clinical cancer …, 2004 - AACR
… Moreover, when looking for a potential biological concentration response effect between
VEGF expression levels and clinical outcome, we were able to demonstrate that absolute levels …

Fibroblast growth factor 23 and adverse clinical outcomes in type 2 diabetes: a bitter-sweet symphony

SMH Yeung, SJL Bakker, GD Laverman… - Current diabetes …, 2020 - Springer
growth factor 23 (FGF23) is a key phosphate-regulating hormone that has been associated
with adverse outcomes in … and outcomes in patients with type 2 diabetes with or without CKD. …

Impact of Epidermal Growth Factor Receptor and KRAS Mutations on Clinical Outcomes in Previously Untreated Non–Small Cell Lung Cancer Patients: Results of an …

DM Jackman, VA Miller, LA Cioffredi, BY Yeap… - Clinical Cancer …, 2009 - AACR
Clinical outcomes were analyzed to look for differences based on EGFR and KRAS genotypes,
as well as clinical … receptor (EGFR) and KRAS mutations on clinical outcomes to EGFR–…

Gene therapy approach with an emphasis on growth factors: theoretical and clinical outcomes in neurodegenerative diseases

DGT Parambi, KS Alharbi, R Kumar, S Harilal… - Molecular …, 2022 - Springer
… Despite the many clinical trials conducted so far, data have shown disappointing outcomes.
The efforts done to improve outcomes, efficacy, and safety in the identification of targets in …

[PDF][PDF] Transforming growth factor‐β gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer

C Coulouarn, VM Factor, SS Thorgeirsson - Hepatology, 2008 - Wiley Online Library
… that showed significant differences in biological properties and clinical outcome (Fig. 5). Thus…
a positive hepatocyte growth factor/c-Met signature and the worst patient outcome. Here we …

The significance of placenta growth factor in angiogenesis and clinical outcome of human gastric cancer

CN Chen, FJ Hsieh, YM Cheng, WF Cheng, YN Su… - Cancer letters, 2004 - Elsevier
… and expression ratio showed similar correlation with clinical outcome. … clinical outcome.
EIA can give an assessment with less sampling bias, and can measure various growth factors

Impact of hormone receptor status on patterns of recurrence and clinical outcomes among patients with human epidermal growth factor-2-positive breast cancer in the …

I Vaz-Luis, RA Ottesen, ME Hughes, PK Marcom… - Breast Cancer …, 2012 - Springer
… on clinical trial data alone. We aimed to describe clinicopathological features, patterns of
recurrence and clinical outcomes of HER2-positive breast cancer according to HR status. …