Biomarkers predicting clinical outcome of epidermal growth factor receptor–targeted therapy in metastatic colorectal cancer
S Siena, A Sartore-Bianchi… - Journal of the …, 2009 - academic.oup.com
… and cetuximab that target the epidermal growth factor receptor (EGFR) have expanded the
… by immunostaining does not reliably predict clinical outcome of EGFR-targeted treatment has …
… by immunostaining does not reliably predict clinical outcome of EGFR-targeted treatment has …
Transforming growth factor β1 is associated with angiogenesis, metastasis, and poor clinical outcome in prostate cancer
P Wikström, P Stattin, I Franck‐Lissbrant… - The …, 1998 - Wiley Online Library
BACKGROUND Prostate tumors express high levels of transforming growth factor‐β1 (TGF‐β1)
and seem to acquire resistance to its antiproliferative effects with tumor progression. …
and seem to acquire resistance to its antiproliferative effects with tumor progression. …
Epidermal growth factor receptor expression in breast cancer association with biologic phenotype and clinical outcomes
… Epidermal growth factor receptor (EGFR) expression is associated with … Clinical and biological
features of EGFR‐positive and EGFR‐negative tumors were compared. Clinical outcomes …
features of EGFR‐positive and EGFR‐negative tumors were compared. Clinical outcomes …
Association between HER-2/neu and Vascular Endothelial Growth Factor Expression Predicts Clinical Outcome in Primary Breast Cancer Patients
GE Konecny, YG Meng, M Untch, HJ Wang… - Clinical cancer …, 2004 - AACR
… Moreover, when looking for a potential biological concentration response effect between
VEGF expression levels and clinical outcome, we were able to demonstrate that absolute levels …
VEGF expression levels and clinical outcome, we were able to demonstrate that absolute levels …
Fibroblast growth factor 23 and adverse clinical outcomes in type 2 diabetes: a bitter-sweet symphony
… growth factor 23 (FGF23) is a key phosphate-regulating hormone that has been associated
with adverse outcomes in … and outcomes in patients with type 2 diabetes with or without CKD. …
with adverse outcomes in … and outcomes in patients with type 2 diabetes with or without CKD. …
Impact of Epidermal Growth Factor Receptor and KRAS Mutations on Clinical Outcomes in Previously Untreated Non–Small Cell Lung Cancer Patients: Results of an …
DM Jackman, VA Miller, LA Cioffredi, BY Yeap… - Clinical Cancer …, 2009 - AACR
… Clinical outcomes were analyzed to look for differences based on EGFR and KRAS genotypes,
as well as clinical … receptor (EGFR) and KRAS mutations on clinical outcomes to EGFR–…
as well as clinical … receptor (EGFR) and KRAS mutations on clinical outcomes to EGFR–…
Gene therapy approach with an emphasis on growth factors: theoretical and clinical outcomes in neurodegenerative diseases
… Despite the many clinical trials conducted so far, data have shown disappointing outcomes.
The efforts done to improve outcomes, efficacy, and safety in the identification of targets in …
The efforts done to improve outcomes, efficacy, and safety in the identification of targets in …
[PDF][PDF] Transforming growth factor‐β gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer
C Coulouarn, VM Factor, SS Thorgeirsson - Hepatology, 2008 - Wiley Online Library
… that showed significant differences in biological properties and clinical outcome (Fig. 5). Thus…
a positive hepatocyte growth factor/c-Met signature and the worst patient outcome. Here we …
a positive hepatocyte growth factor/c-Met signature and the worst patient outcome. Here we …
The significance of placenta growth factor in angiogenesis and clinical outcome of human gastric cancer
CN Chen, FJ Hsieh, YM Cheng, WF Cheng, YN Su… - Cancer letters, 2004 - Elsevier
… and expression ratio showed similar correlation with clinical outcome. … clinical outcome.
EIA can give an assessment with less sampling bias, and can measure various growth factors …
EIA can give an assessment with less sampling bias, and can measure various growth factors …
Impact of hormone receptor status on patterns of recurrence and clinical outcomes among patients with human epidermal growth factor-2-positive breast cancer in the …
I Vaz-Luis, RA Ottesen, ME Hughes, PK Marcom… - Breast Cancer …, 2012 - Springer
… on clinical trial data alone. We aimed to describe clinicopathological features, patterns of
recurrence and clinical outcomes of HER2-positive breast cancer according to HR status. …
recurrence and clinical outcomes of HER2-positive breast cancer according to HR status. …
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