… clinical understanding of uncommon EGFR mutations, but is the first to systematically
categorise and document both response to EGFR-TKIs and survival in this patient … EGFR-mutated …

… )-mutant non-small cell lung cancer (NSCLC) is a rare subset of NSCLC. The aim of this … ,
and clinical outcomes of metastatic NSCLC harboring uncommon EGFR mutation at Thailand’s …

… EGFRm or with rare EGFR mutations not responsive to first-line EGFR TKIs. Analyzed genes
… MassARRAY analysis confirmed EGFR mutations but did not disclose additional mutations. …

… also assessed outcomes in patients categorized by EGFR-TKIs: (1) gefitinib group; (2) erlotinib
group. Results A total of 438 patients with NSCLC harboring uncommon EGFR mutations …

… EGFR-TKIs. We also found that patients with compound mutations and double uncommon
EGFR mutations … ) than those with single uncommon EGFR mutation, although the difference …

… In conclusion, uncommon EGFR mutations may be associated with a poor outcome and the
… in cases of double uncommon mutations and such patients should be treated accordingly. …

… EGFR insertion 20 who received EGFR-TKIs as a 1L treatment. We classified patients with
uncommon EGFR mutation into the major uncommon EGFR … Clinical outcomes of the second-…

… In addition, our results suggest that point mutations in codon … with other uncommon single
or compound mutations; in our … similar efficacy results in single exon 18 point mutations as …

… This study reviewed the prevalence of uncommon EGFR mutations and their sensitivity to
EGFR… L858R mutations, indicating that they may benefit from EGFR-TKIs as a first-line therapy. …

… ), while the rest (referred as uncommon EGFR mutation) have not been fully … investigated
clinical characteristics and outcome of patients with different … 2.2 Clinical outcome assessments …