[PDF][PDF] Strain-and species-level variation in the microbiome of diabetic wounds is associated with clinical outcomes and therapeutic efficacy

LR Kalan, JS Meisel, MA Loesche, J Horwinski… - Cell host & …, 2019 - cell.com
… metagenomics allows for strain-level tracking and functional annotation, which both revealed
aspects of the DFU microbiome and its association with clinical outcomes in this study. …

[HTML][HTML] Host genetic variation and its microbiome interactions within the Human Microbiome Project

R Kolde, EA Franzosa, G Rahnavard, AB Hall… - Genome medicine, 2018 - Springer
… Finally, we assessed associations between host genome and microbiome variation in a
non-targeted manner directly through a genome-wide association study. We performed the …

Association of the sinonasal bacterial microbiome with clinical outcomes in chronic rhinosinusitis: a systematic review

JC Wang, CA Moore, MV Epperson… - International forum of …, 2020 - Wiley Online Library
microbiome in CRS and how it may affect clinical outcomes … from simply defining the
microbiome to utilizing its composition … There is substantial variation in the native microbiome

Microbial diversity in clinical microbiome studies: sample size and statistical power considerations

C Casals-Pascual, A González… - …, 2020 - gastrojournal.org
… enough to be clinically relevant. The prediction of clinical outcomes through microbial
biomarkers … number of participants needed for clinical microbiome studies is a largely unresolved …

Compositional and functional differences in the human gut microbiome correlate with clinical outcome following infection with wild-type Salmonella enterica serovar …

Y Zhang, A Brady, C Jones, Y Song, TC Darton… - MBio, 2018 - Am Soc Microbiol
… the central hypothesis that clinical outcomes may be linked to … clinical outcomes following
exposure to wild-type S. Typhi. … gut microbiota on clinical outcomes following exposure to …

[HTML][HTML] Altered intestinal microbiome and metabolome correspond to the clinical outcome of sepsis

S Sun, D Wang, D Dong, L Xu, M Xie, Y Wang, T Ni… - Critical Care, 2023 - Springer
… In this study, we used a combination of the microbiome and … play important roles in disease
outcome were screened out. Finally, … Our findings may help to predict the clinical outcome of …

[HTML][HTML] Associations between host gene expression, the mucosal microbiome, and clinical outcome in the pelvic pouch of patients with inflammatory bowel disease

XC Morgan, B Kabakchiev, L Waldron, AD Tyler… - Genome biology, 2015 - Springer
… with mucosal microbiomes and clinical outcomes. We … variation was explained by host-microbe
correspondences, in that associations of the host transcriptome with the microbiome were …

Lung microbiota predict clinical outcomes in critically ill patients

RP Dickson, MJ Schultz, T Van Der Poll… - American journal of …, 2020 - atsjournals.org
… of the lung microbiome (… that variation in lung microbiota is predictive of clinical outcomes
in critically ill patients. This key finding is compatible with broader (non-ICU) lung microbiome

[HTML][HTML] Integrated analysis of microbiome and host transcriptome reveals correlations between gut microbiota and clinical outcomes in HBV-related hepatocellular …

H Huang, Z Ren, X Gao, X Hu, Y Zhou, J Jiang, H Lu… - Genome medicine, 2020 - Springer
… of this variation in the composition of gut microbiome [26, 27]. In this study, we provided
evidence that the tumor burden of HCC is associated with the presence of specific gut microbes, …

Pharmacomicrobiomics: the impact of human microbiome variations on systems pharmacology and personalized therapeutics

M ElRakaiby, BE Dutilh, MR Rizkallah… - Omics: a journal of …, 2014 - liebertpub.com
… Below we discuss examples of intra-individual variations that shape the microbiome … how
the concept of a microbiome cloud complicates cataloguing human microbiome variations, their …