Carbon ion therapy: a modern review of an emerging technology

TD Malouff, A Mahajan, S Krishnan, C Beltran… - Frontiers in …, 2020 - frontiersin.org
… radiobiological, physics, and clinical knowledge of CIRT (1–3, … the current clinical literature
for patients treated with carbon ion … to define the role of carbon ion therapy in clinical practice. …

Carbon ion radiotherapy in Japan: an assessment of 20 years of clinical experience

T Kamada, H Tsujii, EA Blakely, J Debus… - The Lancet …, 2015 - thelancet.com
carbon ions, the optimum radiation dose-fractionation pattern for each type of tumour, and
irradiation techniques for the precise delivery of carbon ions. … clinical trials with carbon ion

Bringing the heavy: carbon ion therapy in the radiobiological and clinical context

CD Schlaff, A Krauze, A Belard, JJ O'Connell… - Radiation …, 2014 - Springer
… use of carbon ion therapy for … clinical trials, and recommend which malignancies could be
initial primary targets for the introduction of carbon ion therapy into mainstream clinical practice

A review of update clinical results of carbon ion radiotherapy

H Tsujii, T Kamada - Japanese journal of clinical oncology, 2012 - academic.oup.com
… for itself a solid place in general practice. This review describes clinical results of carbon
ion radiotherapy together with physical, biological and technological aspects of carbon ions. …

Carbon ion radiobiology

W Tinganelli, M Durante - Cancers, 2020 - mdpi.com
… Radiotherapy with carbon ions has been used for over 20 … The physics advantages of carbon
ions compared to X-rays are … -clinical research can impact clinical trials in C-ion therapy. …

Carbon ion radiotherapy: clinical experiences at National Institute of Radiological Science (NIRS)

T Okada, T Kamada, H Tsuji, J Mizoe… - Journal of radiation …, 2010 - academic.oup.com
… In June 1994, the world’s first clinical center offering carbon ion … Among several types of
ion species, carbon ions were chosen for … This article reviews the clinical results of carbon ion

Carbon ion radiotherapy: a review of clinical experiences and preclinical research, with an emphasis on DNA damage/repair

O Mohamad, BJ Sishc, J Saha, A Pompos, A Rahimi… - Cancers, 2017 - mdpi.com
… States alone, and 10 centers treating patients with carbon ions (C-ions) worldwide [6,7]. As
the … pre-clinical and clinical data that demonstrate the increased efficacy of heavy ion therapy …

Assessment of RBE-weighted dose models for carbon ion therapy toward modernization of clinical practice at HIT: in vitro, in vivo, and in patients

S Mein, C Klein, B Kopp, G Magro, S Harrabi… - International Journal of …, 2020 - Elsevier
… In that regard, given the results of this study, carbon ion facilities may consider clinical
implementation of mMKM as either a primary effective dose model or in conjunction with currently …

Integration and evaluation of automated Monte Carlo simulations in the clinical practice of scanned proton and carbon ion beam therapy

J Bauer, F Sommerer, A Mairani… - Physics in Medicine …, 2014 - iopscience.iop.org
… the use of MC for scanned ion beams, especially carbon ions, we believe that this contribution
… to introduce pencil beam scanning with protons and heavier ions in the clinical practice. …

Clinical results of carbon ion radiotherapy at NIRS

H Tsujii, J Mizoe, T Kamada, M Baba… - Journal of radiation …, 2007 - ieeexplore.ieee.org
… Among several types of ion species, we have chosen carbon ions for cancer therapy because
… evolution of carbon ion radiotherapy over the last decade and highlights the clinical results …