… , as well as more recent findings on its role in amplifying signaling … clinical features of DOCK8
deficiency, and highlight the emergence of a family of DOCK-related immune deficiencies, …

… Because of a lack of additional clinical features to support a diagnosis of DOCK8 deficiency,
… as likely to have been affected with DOCK8 deficiency. No DNA samples were available …

… clinical features of this disease to studies using patients’ cells and a mouse model of Dock8
deficiency, which have revealed how DOCK8 … the absence of DOCK8 contributes to patients’ …

… , STAT3 deficient patients lack the profound immunodeficiency found in DOCK8 deficiency
[… syndrome shares remarkably many clinical features with DOCK8 deficiency such as eczema, …

… clinical features of Job Syndrome and DOCK8 deficiency and found that in DOCK8 deficiency,
coarse facial features … facial features should not necessarily exclude DOCK8 deficiency. …

… When the cardinal features of Job's syndrome or DOCK8 deficiency are present, it may
be possible to make a diagnosis based on clinical findings alone (Table 3). However, early …

… same gene (DOCK8), we recognized that their disorders shared certain clinical features with
… Besides lymphopenia, DOCK8 deficiency has manifestations that have not previously been …

… The patients [F3P3, F6P2, F6P3 and F7P2] were considered Dock8 deficient since they
have siblings with confirmed DOCK8 mutation and similar clinical presentation but no available …

… ), sometimes termed DOCK8 deficiency, has been previously reviewed elsewhere.1-3
DIDS is a combined immunodeficiency that has several unusual clinical features (see pictorial …

… DOCK8 deficiency to present as an immune dysregulatory disorder that overlaps in its phenotype
with IPEX-like disorders [21], underscoring the vital function of DOCK8 … clinical findings …