… However, it is worth stressing that the sensitivity of HRCT in identifying limited lung disease
which is not necessarily clinically significant has posed the major management problem of …

… Stagnaro etal79 studied lymphocytes collected from healthy volunteers and from patients
with chronic lung disease. When these lymphocytes were exposed to reactive oxygen species …

… differences may be statistically significant but not clinically significant. How much does the …
chronic obstructive pulmonary disease (COPO)? We studied individuals with stable COPD(n =…

… for lung diseases. AIM: In this review, we aimed to investigate the effects of diabetes and
hypoglycemic agent on lung diseases, … However, the clinical significance is unknown, mostly be…

… , each patient had a clinical diagnosis of chronic obstructive lung disease with severe
hypoxemia (… therapy or had diseases other than chronic obstructive lung disease that might affect …

… obstructive lung disease. Prospective studies of patients with clinically significant airways …
A poor prognosis for patients with chronic obstructive lung disease has been shown to be …

… distance as the primary indicator of clinically significant change. Although many authors have
… In conclusion, this study demonstrates that the threshold for clinically significant change in …

… Clinically significant depression symptoms are seen in almost half of patients with COPD,
and about 20% of patients will meet psychiatric criteria for major depressive or dysthymic …

… For example, patients with anti-topoisomerase antibodies are more likely to develop clinically
significant lung fibrosis and those with anti-RNA polymerase III antibodies less likely. Other …

… In patients with clinically significant disease, two main types of clinical presentations have
been observed. The first is characterized by subacute onset of dyspnea and widespread …