… permeability of the producer strain. beta-Lactamases sometimes cause obvious resistance to
… of the prevalent beta-lactamases to cause resistance to widely used beta-lactams, whether …

… Control of ~-lactamase activity in the growing cell is another … of ~ lactamases in the
development of resistant strains. In this … biochemist's approach with the clinical microbiologist's …

… This debated question is addressed and the novel β-lactam-β-lactamase … strains that
carry multiple different classes of β-lactamases is to switch the β-lactam partner of a clinically …

… The OXA-24 β-lactamase hydrolyzed benzylpenicillin and cephaloridine but lacked activity
… extract of this transformant strain. Therefore, we consider this new β-lactamase to be involved …

… betalactamase mediated resistance to most of the beta-lactam … isolate that expresses multiple
βlactamase enzymes, further … spectrum beta-lactamase( ESBL) status of these strains was …

… The aim of this study was to test the hypothesis that β-lactamase TEM-1 is responsible for …
the 17 clinical strains. The MICs of sulbactam and other β-lactams for these strains are shown …

… strains that produce acquired class B metallo-β-lactamases (… Although these β-lactamase
types share less than 40% amino … VIM-1 MBL gene, found in a clinical strain of P. aeruginosa. …

… coli and Proteus mirabilis strains that encode for inhibitor-resistant β-lactamases (IRT) or …
or sulbactam against IRT strains.[5] Despite the limitations of β-lactam/inhibitor combinations in …

… AmpC (β-lactamase activities were 12- to 657-fold higher than those of the parent strains), but
… frequent mechanism of AmpC hyperproduction in clinical strains, our findings suggest that …

… Most strains of enterobacteria andPseudomonas aeruginosa produce chromosomally-… -lactamases.
When synthesized copiously these enzymes cause resistance to almost allβ-lactams, …