3D-bioprinted human tissue and the path toward clinical translation
… a tailored approach to tissue and organ engineering. In … human tissue and the proof-of-concept
applications that address long-standing challenges on the path toward clinical translation…
applications that address long-standing challenges on the path toward clinical translation…
Chasing the paradigm: clinical translation of 25 years of tissue engineering
T Hoffman, A Khademhosseini… - Tissue Engineering Part …, 2019 - liebertpub.com
… to the development and clinical translation of tissue engineering-inspired therapies, leading
… that facilitate tissue functional recovery. The foundation of tissue engineering involves the …
… that facilitate tissue functional recovery. The foundation of tissue engineering involves the …
Tissue engineered constructs: perspectives on clinical translation
… The field of tissue engineering and regenerative medicine is rapidly expanding, both in …
and in clinical translation.5 The development of tissue engineering scaffolds for clinical use has …
and in clinical translation.5 The development of tissue engineering scaffolds for clinical use has …
In vitro platforms for tissue engineering: implications for basic research and clinical translation
J Rouwkema, S Gibbs, MP Lutolf… - Journal of tissue …, 2011 - Wiley Online Library
… Clinical translation of engineered tissues into regenerative medicine applications, and the …
, result in an increasing demand for human tissues engineered in vitro for implantation, in vitro …
, result in an increasing demand for human tissues engineered in vitro for implantation, in vitro …
Current challenges of bioprinted tissues toward clinical translation
… In summary, the use of bioprinting for biofabrication of human tissues for transplantation has
developed substantially over the past decade. Many studies have demonstrated promising …
developed substantially over the past decade. Many studies have demonstrated promising …
Concise review: mind the gap: challenges in characterizing and quantifying cell-and tissue-based therapies for clinical translation
EA Rayment, DJ Williams - Stem Cells, 2010 - academic.oup.com
… before reaching clinical trials, especially in terms of whether in vitro efficacy tests will act as
successful surrogates for predicting in vivo human clinical response. Clinical endpoints have …
successful surrogates for predicting in vivo human clinical response. Clinical endpoints have …
Human adipose-derived cells: an update on the transition to clinical translation
… The pace of discovery involving adipose-derived cells continues to accelerate at both the
preclinical and clinical translational levels. Adipose tissue is a source of freshly isolated, …
preclinical and clinical translational levels. Adipose tissue is a source of freshly isolated, …
A perspective on the clinical translation of scaffolds for tissue engineering
… Finally, we hope to provide insight into the clinical translation of technologies rooted in tissue
… on the road to translation, and the path forward for promising technologies in development. …
… on the road to translation, and the path forward for promising technologies in development. …
Advances in skin tissue bioengineering and the challenges of clinical translation
BL Dearman, ST Boyce, JE Greenwood - Frontiers in Surgery, 2021 - frontiersin.org
… In time, these technologies and advances in tissue engineering will at least reduce, and
possibly replace, the need for skin autografts and enable easier clinical translation of an …
possibly replace, the need for skin autografts and enable easier clinical translation of an …
Clinical translation in tissue engineering—the surgeon's view
CE Dlaska, G Andersson, M Brittberg… - Current Molecular …, 2015 - Springer
… clinical translation needs relevant pre-clinical models, which provides similar anatomy and
comparable size translation, like in the clinical … surgeons to use it in the clinical human model. …
comparable size translation, like in the clinical … surgeons to use it in the clinical human model. …
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