Challenges in clinical trials for children and young people

FB Lagler, S Hirschfeld, JM Kindblom - Archives of Disease in …, 2021 - adc.bmj.com
clinical trials is required in both designing, planning, co-ordinating and organising paediatric
clinical trials, as well as research … Strengthening of paediatric clinical research is essential …

Prerequisites to support high-quality clinical trials in children and young people

S Hirschfeld, FB Lagler, JM Kindblom - Archives of Disease in …, 2021 - adc.bmj.com
… The rationale and justification for clinical trials in general, and especially clinical trials enrolling
children, is that this is the most valid way to obtain the data needed for decision making.3 …

Involving children and young people in clinical research through the forum of a European Young Persons' Advisory Group: needs and challenges

S Gaillard, S Malik, J Preston… - … & clinical …, 2018 - Wiley Online Library
… the needs for involving children and young people in clinical research, highlighting the …
when designing pediatric research, and how a network such as the European Young Persons’ …

Young people's experiences of participation in clinical trials: reasons for taking part

M Luchtenberg, E Maeckelberghe… - The American Journal …, 2015 - Taylor & Francis
… The purpose of this study was to understand the experiences and motivations of young
people who took part in clinical trials. This is a qualitative interview study of 25 young people

[HTML][HTML] … of delivering digital clinical trials: lessons learned from a randomised controlled trial of an online behavioural intervention for children and young people

CL Hall, C Sanderson, BJ Brown, P Andrén, S Bennett… - Trials, 2020 - Springer
clinical trials have been traditionally conducted in a clinical face-to-face setting, since the late
1990s, there has been an increasing trend towards online or digital trials [… number of trials

[HTML][HTML] Development of a core outcome set for clinical trials in childhood asthma: a survey of clinicians, parents, and young people

IP Sinha, R Gallagher, PR Williamson, RL Smyth - Trials, 2012 - Springer
… fact that only small numbers of young people were included in our study in phase 1. We feel,
however, that our results are relevant to a high proportion of clinical trials, which are usually …

Supporting children and young people when making decisions about joining clinical trials: qualitative study to inform multimedia website development

…, J Preston, DH Taylor, P Baines, B Young - BMJ open, 2019 - bmjopen.bmj.com
… interview and focus group study with children, young people, parents and professionals to
… in paediatric clinical trials. This study was part of the TRials Engagement in Children and …

The challenges of clinical trials for adolescents and young adults with cancer

A Ferrari, M Montello, T Budd… - Pediatric blood & …, 2008 - Wiley Online Library
… United Kingdom, older adolescents with ALL treated on pediatric clinical trials have fared …
on adult leukemia treatment trials 8-14. In Germany, older adolescents with Ewing sarcoma …

Guidance on clinical research involving infants, children and young people: an update for researchers and research ethics committees

N Modi, J Vohra, J Preston, C Elliott… - Archives of disease in …, 2014 - adc.bmj.com
… The ethical principles underpinning the participation of children in clinical research have …
, greater involvement of young people and parents in all aspects of research, and appreciation …

Should We Tell Children and Young People About the Positive Experience of Taking Part in Clinical Trials?

M Spriggs - The American Journal of Bioethics, 2015 - Taylor & Francis
… of the children and young people in this study understand the importance of research and
… and when in the recruitment process of children and young people. For instance, what is the …