… In conclusion, ot implantation of human prostate cancer cells into nude mice leads to the
reproducible formation of lymph node and lung metastases, and is superior to the sc technique. …

… The PCMWG reviewed the state of prostate cancer preclinical models and … mouse models
that have hampered the transition of scientific findings from these models to human clinical …

… xenograft mouse model for human prostate cancer respecting … as relevant markers of both
metastatic competence in mice … of Mgat5b in prostate cancer indicating a significant biologic …

… for analysis of animal models of prostate cancer, lessons learned since the last consensus
meeting, and emerging themes in the pathology of mouse models of prostate cancer. …

… diverse molecular subtypes of prostate cancer. In addition, several animal models have
been developed to demonstrate the etiological molecular basis of the prostate cancer. In recent …

… of human prostate cancer remain largely undefined. It is difficult to investigate stages in the
development of human prostate cancer, but some animal models provide opportunities inthis …

… The characterization of animal models has indicated that the … to develop prostate inflammatory
lesions and prostate cancer (… subset of PC patients limiting thereby their clinical relevance. …

… permutations, and p < 0.05 was considered significant. To estimate clinical relevance, we
used a Cox proportional hazards model for univariate analysis and Kaplan-Meier survival …

… Thus, rats given MNU and chronic testosterone represent a relevant and reliable model
for … are now adequate animal models for prostate cancer proven to be suitable for preclinical …

… models has allowed investigators to delineate the molecular and pathological diversity of
prostate cancer and generated clinically relevant tools to test new therapeutic regimens …