Protective effects of total flavonoids from Clinopodium chinense (Benth.) O. Ktze on myocardial injury in vivo and in vitro via regulation of Akt/Nrf2/HO-1 pathway

HJ Zhang, RC Chen, GB Sun, LP Yang, XD Xu, XB Sun - Phytomedicine, 2018 - Elsevier
… However, no study has been conducted about the protective effects of TFCC on I/R-induced
myocardial injury. In the present study, we examined the protective effects of TFCC against …

Total Flavonoids from Clinopodium chinense (Benth.) O. Ktze Protect against Doxorubicin‐Induced Cardiotoxicity In Vitro and In Vivo

RC Chen, XD Xu, X Zhi Liu, GB Sun… - Evidence‐Based …, 2015 - Wiley Online Library
… Doxorubicin has cardiotoxic effects that limit its clinical benefit in cancer patients. This study
aims to investigate the protective effects of the total flavonoids from Clinopodium chinense (…

Protective effects of total flavonoids from Clinopodium chinense (Benth.) O. Ktze on myocardial injury in vivo and in vitro via regulation of Akt/Nrf2/HO-1 pathway.

ZHJ Zhang HaiJing, CRC Chen RongChang… - 2018 - cabidigitallibrary.org
… Purpose: The aim of the study was to study the protective effects and possible mechanism
of TFCC against isoproterenol (ISO)-mediated myocardial injury in vivo and anoxia/…

Extract of Clinopodium chinense Inhibits High Glucose–Induced Apoptosis in Human Umbilical Vein Endothelial Cells

J Li, F Wu, K Chen, J Liang, S Ma - Journal of cardiovascular …, 2013 - journals.lww.com
… the protective effects of Clinopodium chinense extract (CCE) … results demonstrate that the
antiapoptotic effect of CCE was … an important role in protecting endothelial cell by inhibiting …

Two new flavonoid–triterpene saponin meroterpenoids from Clinopodium chinense and their protective effects against anoxia/reoxygenation-induced apoptosis in …

YD Zhu, RC Chen, H Wang, H Jiang, XL Huang… - Fitoterapia, 2018 - Elsevier
… Kuntze showed significantly protective effect against doxorubicin-induced cardiotoxicity and
… of Clinopodium chinense [13]. In the present study, we examined the protective effects of two …

Tournefolic acid B, derived from Clinopodium chinense (Benth.) Kuntze, protects against myocardial ischemia/reperfusion injury by inhibiting endoplasmic reticulum …

Y Yu, N Xing, X Xu, Y Zhu, S Wang, G Sun, X Sun - Phytomedicine, 2019 - Elsevier
… In this study, we elucidated the significant protective effects of … Determination the protective
effects of TAB on myocardial I/R … the clinical application of Clinopodium chinense (Benth.) …

[HTML][HTML] Protective effect of Clinopodium chinense (Benth.) O. Kuntze against abnormal uterine bleeding in female rats

L Li, Q Huang, X Duan, L Han, D Peng - Journal of Pharmacological …, 2020 - Elsevier
… Pharmacopoeia (2015), and it produces anti-inflammatory effects by the inhibition of NO
and TNF-α production. Quercetin showed a good protective effect on subarachnoid …

Phenolic Compounds from Clinopodium chinense (Benth.) O. Kuntze and Their Inhibitory Effects on α‐Glucosidase and Vascular Endothelial Cells Injury

B Zeng, K Chen, P Du, SS Wang, B Ren… - Chemistry & …, 2016 - Wiley Online Library
… inhibitory activity and protective effect on vascular endothelial … 11 showed significant
protective effect on endothelial cells … showed weak protective effect with their protective rate less …

Protective effect of the total flavonoids from Clinopodium chinense against LPS-induced mice endometritis by inhibiting NLRP3 inflammasome-mediated pyroptosis

L Li, J Qi, H Tao, L Wang, L Wang, N Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Clinopodium chinense (Benth.) O. Kuntze (C. chinense) is
a Chinese herbal medicine used in treating gynecological hemorrhagic diseases for …

Clinoposides A–F: Meroterpenoids with protective effects on H9c2 cardiomyocyte from Clinopodium chinense

YD Zhu, HF Wu, GX Ma, RC Chen, HL Long, ZL Zuo… - RSC …, 2016 - pubs.rsc.org
… The protective effects of clinoposides A–F against H 2 O 2 -… effects, clinoposides B, D and
F showed better protective … 1) and their protective effects against H 2 O 2 -induced H9c2 …